α-Tocopherol and Ascorbic Acid in Early Postoperative Period of Cardiopulmonary Bypass
To investigate whether α-tocopherol and ascorbic acid have effect on the suppression of inflammation in the early postoperative period after open heart surgery.
Processed Residual Pump Blood in Cardiac Surgery: The Processed Residual Blood in Cardiac Surgery Trial
Ultrafiltration of residual CPB volume in adults undergoing isolated CABG surgery does not reduce the need for transfusion or bleeding.
Prospective Validation of the Vasoactive-Inotropic Score and Correlation to Short-Term Outcomes in Neonates and Infants after Cardiothoracic Surgery
In neonates and infants, a higher VIS at 48 h after cardiothoracic surgery is strongly associated with increased length of ventilation, and prolonged ICU and total hospital stay.
Preservation Solution Supplemented with Biliverdin Prevents Lung Cold Ischaemia/Reperfusion Injury
This study demonstrates that the exposure of the lung grafts to BV during cold storage can impart potent cytoprotective effects to lung cold ischaemia/reperfusion injury and significantly improve the lung graft function following extended cold preservation and transplantation by the mechanism of a reduction in oxidative injury and following inflammatory events.
Fluid Balance as an Early Indicator of Acute Kidney Injury in CV Surgery
We hypothesized that positive fluid balance (FB) is the result of intraoperative kidney injury and associated renal vasoconstriction, and therefore may be an early clinical indicator of acute kidney injury (AKI).
Longer Blood Storage is Associated with Suboptimal Outcomes in High-Risk Pediatric Cardiac Surgery
The freshest RBC units available should be used for pediatric cardiac operations expected to require more than 4 units or more than 150 mL/kg of allogeneic RBC transfusions, with no units more than 14 days old being transfused whenever possible.
Use of Prothrombin Complex Concentrate for Excessive Bleeding after Cardiac Surgery
Administration of low-dose of PCC significantly decreased postoperative bleeding after CPB.
Haemostatic Therapy in Coronary Artery Bypass Graft Patients with Decreased Platelet Function: Comparison of Fibrinogen Concentrate with Allogeneic Blood Products
Fibrinogen concentrate administration increased the fibrin clot quality and helped achieve haemostasis.
A Pilot Feasibility Trial of Allocation of Freshest Available Red Blood Cells versus Standard Care in Critically Ill Patients
We aimed to evaluate in intensive care unit (ICU) patients 1) the feasibility of allocating freshest available compatible RBCs versus standard care and 2) the suitability of this approach in the design of a large randomized controlled trial (RCT).
Changes in Microvascular Reactivity after Cardiopulmonary Bypass in Patients with Poorly Controlled versus Controlled Diabetes
Poorly controlled diabetes results in impaired arteriolar function before and after CPB.
Decreased Coronary Microvascular Reactivity after Cardioplegic Arrest in Patients with Uncontrolled Diabetes Mellitus
Uncontrolled diabetes is associated with endothelium-dependent and -independent vascular dysfunction of coronary arterioles.
Prolonged Central Venous Desaturation Measured by Continuous Oximetry is Associated with Adverse Outcomes in Pediatric Cardiac Surgery
We demonstrate that ScvO₂ desaturations by continuous oximetry are associated with major adverse events in pediatric patients undergoing cardiac surgery.