Fresh Red Blood Cell Transfusion and Short-Term Pulmonary, Immunologic, and Coagulation Status: A Randomized Clinical Trial
In this randomized clinical trial, no differences were noted in early measures of pulmonary function or in immunologic or coagulation status when comparing fresh versus standard issue single-unit RBC transfusion.
Microparticles from Stored Red Blood Cells Activate Neutrophils and Cause Lung Injury after Hemorrhage and Resuscitation
The presence of MPs in stored units can be associated with adverse effects, including lung injury, after transfusion.
Peroperative Effects of Fresh Frozen Plasma and Antithrombin III on Heparin Sensitivity and Coagulation during Nitroglycerine Infusion in Coronary Artery Bypass Surgery
ATIII may be preferred to FFP in patients with heparin resistance due to NTG infusion undergoing CABGS.
The Age of Blood Evaluation (ABLE) Randomized Controlled Trial: Study Design
The "Age of Blood Evaluation" (ABLE) study (ISRCTN44878718) is a double-blind, multicenter, parallel randomized controlled clinical trial.
Effect of Hospital Culture on Blood Transfusion in Cardiac Procedures
We sought to quantitate the contribution of hospital influence on individual surgeons' transfusion practices.
Insufflation of Hydrogen Gas Restrains the Inflammatory Response of Cardiopulmonary Bypass in a Rat Model
We suggest that H(2) insufflation is a possible new potential therapy for counteracting CPB-induced systemic inflammation.
What Blood Temperature for an Ex Vivo Extracorporeal Circuit?
Investigators in this field must be aware of the fact that blood temperature is a crucial confounding parameter and the type of "background noise" they will face depending on the strategy adopted.
Selective Pulmonary Pulsatile Perfusion with Oxygenated Blood During Cardiopulmonary Bypass Attenuates Lung Tissue Inflammation but Does Not Affect Circulating Cytokine Levels
Improved respiratory outcome has been shown after selective pulsatile pulmonary perfusion (sPPP) during cardiopulmonary bypass (CPB).
α-Tocopherol and Ascorbic Acid in Early Postoperative Period of Cardiopulmonary Bypass
To investigate whether α-tocopherol and ascorbic acid have effect on the suppression of inflammation in the early postoperative period after open heart surgery.
Processed Residual Pump Blood in Cardiac Surgery: The Processed Residual Blood in Cardiac Surgery Trial
Ultrafiltration of residual CPB volume in adults undergoing isolated CABG surgery does not reduce the need for transfusion or bleeding.
Prospective Validation of the Vasoactive-Inotropic Score and Correlation to Short-Term Outcomes in Neonates and Infants after Cardiothoracic Surgery
In neonates and infants, a higher VIS at 48 h after cardiothoracic surgery is strongly associated with increased length of ventilation, and prolonged ICU and total hospital stay.
Fluid Balance as an Early Indicator of Acute Kidney Injury in CV Surgery
We hypothesized that positive fluid balance (FB) is the result of intraoperative kidney injury and associated renal vasoconstriction, and therefore may be an early clinical indicator of acute kidney injury (AKI).