Haemostatic Therapy in Coronary Artery Bypass Graft Patients with Decreased Platelet Function: Comparison of Fibrinogen Concentrate with Allogeneic Blood Products
Fibrinogen concentrate administration increased the fibrin clot quality and helped achieve haemostasis.
A Pilot Feasibility Trial of Allocation of Freshest Available Red Blood Cells versus Standard Care in Critically Ill Patients
We aimed to evaluate in intensive care unit (ICU) patients 1) the feasibility of allocating freshest available compatible RBCs versus standard care and 2) the suitability of this approach in the design of a large randomized controlled trial (RCT).
Changes in Microvascular Reactivity after Cardiopulmonary Bypass in Patients with Poorly Controlled versus Controlled Diabetes
Poorly controlled diabetes results in impaired arteriolar function before and after CPB.
Decreased Coronary Microvascular Reactivity after Cardioplegic Arrest in Patients with Uncontrolled Diabetes Mellitus
Uncontrolled diabetes is associated with endothelium-dependent and -independent vascular dysfunction of coronary arterioles.
Prolonged Central Venous Desaturation Measured by Continuous Oximetry is Associated with Adverse Outcomes in Pediatric Cardiac Surgery
We demonstrate that ScvO₂ desaturations by continuous oximetry are associated with major adverse events in pediatric patients undergoing cardiac surgery.
Advances in Mechanical Circulatory Support in the Treatment of Heart Failure
In recent years, the implantation of Ventricular Assist Devices (VAD) as definitive therapy (DT) has emerged as a promising replacement therapy for heart transplantation.
The Pharmacotherapy Implications of Ventricular Assist Device in the Patient with End-Stage Heart Failure
A basic understanding of this unique therapy can assist pharmacists in attending to the needs of patients with VAD.
Hydrogen as Additive of HTK Solution Fortifies Myocardial Preservation in Grafts with Prolonged Cold Ischemia
Hydrogen as additive of HTK solution fortifies HTK's preservation efficacy for cardiac grafts subjected to prolonged cold ischemia by inhibiting cold ischemia-induced up-regulation of oxidative stress, inflammation mediators, and apoptosis.
Acute Hyponatremia after Cardioplegia by Histidine-Tryptophane-Ketoglutarate–A Retrospective Study
Acute hyponatremia during cardioplegia with HTK solution is isotonic and should probably not be corrected without presence of hypotonicity as confirmed by measurement of serum osmolality.
Preservation of Myocardium During Coronary Artery Bypass Surgery
In the present review article on myocardial protection in contemporary coronary artery bypass surgery, we attempt to elucidate the clinical problems, summarize the outcomes of selected phase III trials, and introduce new perspectives.
Discontinuation of HeartWare RVAD Support without Device Removal in Chronic BIVAD Patients
The HeartWare HVAD used as an RVAD may be stopped and left in place without complications.
Anticoagulation and Bleeding in Patients with Ventricular Assist Devices: Walking the Tightrope
A left ventricular assist device (LVAD) is a lifesaving therapy for end-stage heart failure, but it is associated with major complications such as bleeding and thrombosis.