Fenoldopam and Acute Renal Failure in Cardiac Surgery: A Meta-Analysis of Randomized Placebo-Controlled Trials
This analysis suggests that fenoldopam reduces acute kidney injury in patients undergoing cardiac surgery.
Transfusion Thresholds and other Strategies for Guiding Allogeneic Red Blood Cell Transfusion
The purpose of this review is to compare clinical outcomes in patients randomised to restrictive versus liberal transfusion thresholds (triggers).
Effects of Pre-Storage Leukoreduction on Stored Red Blood Cells Signaling: A Time-Course Evaluation from Shape to Proteome
The introduction of pre-storage leukoreduction in the preparation of standard RBCs intended for transfusion provided significant improvement in the quality of labile products and their post transfusion viability and effects, although the literature data are controversial.
Transfusion Immunomodulation – The Case for Leukoreduced and (Perhaps) Washed Transfusions
The present review will focus on two approaches, leukoreduction and saline washing, as means to reduce adverse transfusion outcomes.
Effect of Fresh Red Blood Cell Transfusions on Clinical Outcomes in Premature, Very Low-Birth-Weight Infants: The ARIPI Randomized Trial
In this trial, the use of fresh RBCs compared with standard blood bank practice did not improve outcomes in premature, very low-birth-weight infants requiring a transfusion.
Reduction of Chronic Graft Injury with a New HTK-Based Preservation Solution in a Murine Heart Transplantation Model
The new HTK-based solution reduces the chronic isograft injury.
Performance Evaluation of a Pediatric Viscous Impeller Pump for Fontan Cavopulmonary Assist
A VIP will augment Fontan cavopulmonary flow in the proper pressure and flow ranges, with low hemolysis risk under more stringent pediatric scale and physiology compared with adult scale.
Cost-Effectiveness of the Implantable HeartMate II Left Ventricular Assist Device for Patients Awaiting Heart Transplantation
Although HeartMate II LVAD implantation significantly increases survival compared with conventional medical management, it does not provide good value for the money spent according to established thresholds of cost-effectiveness in the UK.
New Innovative Instruments Facilitate Both Direct-Vision and Endoscopic-Assisted Mini-Mitral Valve Surgery
Newly innovated mini-mitral valve surgical instruments and techniques facilitate both direct-vision and endoscopic-assisted approaches and accomplish a favorable surgical outcome even in the complex pathology of mitral valve insufficiency.
Practical Considerations of Percutaneous Ventricular Assist Devices
Percutaneous ventricular assist devices are increasingly used today, allowing the scope of left ventricular support to move out of the operating room and into the interventional suite and cardiovascular care unit.
Low Incidence of Bleeding-Related Morbidity with Left Ventricular Assist Device Implantation in the Current Era
The potential to reduce bleeding reduces invasiveness of LVAD surgery, reduces allosensitization, may improve outcomes, and may increase mainstream acceptability of LVADs as definitive therapy for heart failure.
Advances in Mechanical Circulatory Support in the Treatment of Heart Failure
In recent years, the implantation of Ventricular Assist Devices (VAD) as definitive therapy (DT) has emerged as a promising replacement therapy for heart transplantation.