Predictive Value of Perioperative Near-Infrared Spectroscopy for Neurodevelopmental Outcomes after Cardiac Surgery in Infancy
The study objective was to expand on prior research examining intraoperative regional cerebral oxygen saturation (rSO(2)) measured by near-infrared spectroscopy (NIRS) by evaluating the predictive value of perioperative NIRS monitoring for neurodevelopmental outcomes after infant cardiac surgery.
Impact of Experimental Haemodilution on Platelet Function, Thrombin Generation and Clot Firmness: Effects of Different Coagulation Factor Concentrates
The haemostatic alterations caused by haemodilution are multifactorial and affect both blood cells and coagulation.
In Vitro Comparison of Two Different Methods of Cell Washing
The objective of this study was to compare the product created by washing a unit of RBCs with the AutoLog autotransfusion device in the operating room to the washed products from a standard cell washer in the blood bank.
Comparison of Modified Chandler, Roller Pump, and Ball Valve Circulation Models for in vitro Testing in High Blood Flow Conditions: Application in Thrombogenicity Testing of Different Materials for Vascular Applications
Three different models, a modified Chandler loop, roller pump, and a new ball valve model (Hemobile), were compared with regard to intrinsic damage of blood components and activation of platelets.
Wet-Priming Extracorporeal Membrane Oxygenation Device Maintains Sterility for up to 35 Days of Follow-Up
Sterility was maintained in the ECMO circuits for up to 35 days.
Contemporary Results of Open Aortic Arch Surgery
Open aortic arch replacement can be performed with low operative mortality and stroke rates, especially in elective circumstances, by a team with particular focus on the procedure.
Nutritional Imbalances during Extracorporeal Life Support
The aim of this chapter is to describe the changes induced by artificial membranes and the required therapies to optimize nutritional support.
O2 Delivery and CO2 Production during Cardiopulmonary Bypass as Determinants of Acute Kidney Injury
The experimental hypothesis was that nadir DO2 values and nadir DO2/VCO2 ratios during CPB would be independent predictors of AKI.
Preload Sensitivity in Cardiac Assist Devices
In this review, we stratify the preload sensitivity of 17 implantable cardiac assist devices relative to the native heart and discuss the effect of preload sensitivity on left ventricular volume unloading, levels of cardiac support, and the future development of continuous-flow total artificial heart technology.
A Quantitative Comparison of Mechanical Blood Damage Parameters in Rotary Ventricular Assist Devices: Shear Stress, Exposure Time and Hemolysis Index
In this study, computational fluid dynamics (CFD) was used to calculate the hemodynamics in three clinical VADs and two investigational VADs and the shear stress, residence time, and hemolysis were investigated.
Regenerating New Heart with Stem Cells
This article discusses current understanding of myocardial biology, emphasizing the regeneration potential of the adult human heart and the mechanisms involved.
Variations in the Application of Various Perfusion Technologies in Great Britain and Ireland–A National Survey
This study investigates variations in the application of these technologies throughout Great Britain and Ireland (GB & I).