Red Blood Cell Transfusion Volume and Mortality among Patients Receiving Extracorporeal Membrane Oxygenation
Greater red blood cell transfusion volumes among patients supported with ECMO for non-cardiac indications are independently associated with an increase in odds of mortality.
Perioperative Coagulation Management During Cardiac Surgery
Recent studies suggest that implementation of point-of-care testing in hemotherapy algorithms which inclose stepwise therapeutic escalation may reduce perioperative blood loss and the transfusion rate of allogenic blood products. This should improve patient's clinical outcome and reduce costs.
Predictive Modeling of the Virtual Hemi-Fontan Operation for Second Stage Single Ventricle Palliation: Two Patient-Specific Cases
Results demonstrate that the same operation performed in two different patients can lead to different hemodynamic characteristics, and that modeling can be used to uncover physiologic changes associated with different clinical conditions.
A Hemolysis Study of an Intravascular Blood Cooling System for Localized Organ Tissue Cooling
To assess initial blood safety of our new organ cooling system, the CoolGuide Cooling System (CCS), we investigated safe operating conditions and configurations from a hemolysis perspective.
Sternal Closure with Rigid Plate Fixation Versus Wire Closure: A Randomized Controlled Multicenter Trial
Sternal reconstruction using rigid fixation with plates improved bone healing and reduced early postoperative pain compared with wire cerclage.
Beta-Adrenergic Receptor Polymorphisms and Cardiac Graft Function in Potential Organ Donors
We hypothesized that βAR polymorphisms predispose donor hearts to LV dysfunction after brain death.
Update on Blunt Thoracic Aortic Injury: Fifteen-Year Single-Institution Experience
We report our experience with blunt thoracic aortic injury at a level 1 trauma center over the past 15 years.
A Pilot Study Comparing Two Polymethylpentene Extracorporeal Membrane Oxygenators
We compared two polymethylpentene oxygenators being used in our unit: the Maquet Quadrox-iD paediatric® and the Medos Hilite 800LT®.
Does Anemia Impact Hospital Readmissions after Coronary Artery Bypass Surgery
We conducted a single-center retrospective study of 2102 patients who had CABG in Ontario to determine whether anemia at hospital discharge was associated with increased 30-day hospital readmissions, readmission secondary to cardiac disease, and 30-day mortality using administrative data.
Evaluation of the New Generation Dual-Lumen Catheter for Neonatal ECMO
The purpose of this study was to compare the newly designed dual-lumen venovenous catheter (VR13, OriGen Biomedical, Austin, TX) with the current dual-lumen catheter (VV12, OriGen Biomedical).
The Preventative Role of Curcumin on the Lung Inflammatory Response Induced by Cardiopulmonary Bypass in Rats
We designed this study to determine whether or not curcumin inhibits TLR4 and MyD88 protein levels and ameliorates lung inflammatory injury in a rat CPB model.
Factors Predicting Emergency Surgery in Severe Mitral Regurgitation Following Mitral Balloon Valvotomy
The study aim was to identify factors that would predict severe acute MR leading to severe hemodynamic compromise requiring emergency MVR.