Aprotinin Revisited
The present review revisits the aprotinin controversy.
Pharmacokinetics of Tranexamic Acid in Patients Undergoing Cardiac Surgery with Use of Cardiopulmonary Bypass
We conducted a study to assess pharmacokinetics of high-dose tranexamic acid for 24 h after administration of the drug in patients undergoing cardiac surgery with cardiopulmonary bypass.
Perioperative Red Blood Cell Transfusion: Harmful or Beneficial to the Patient?
This review focuses on the physiology of oxygen transport, the hazards of acute anemia, the hazards of RBC transfusion, and the literature putting these problems into perspective.
Early Platelet Dysfunction: An Unrecognized Role in the Acute Coagulopathy of Trauma
In this study, we show that platelet dysfunction is manifest after major trauma and before substantial fluid or blood administration.
Analytical Performance Evaluation of Four Cartridge-Type Blood Gas Analyzers
Globally, all four cartridge-type blood gas analyzers produced clinically acceptable results.
An Original Model to Predict Intensive Care Unit Length-of Stay after Cardiac Surgery in a Competing Risk Framework
ICU-LOS can be predicted by preoperative data and type of surgeries.
Hyperfibrinolysis is Common in Out-of-Hospital Cardiac Arrest: Results from a Prospective Observational Thromboelastometry Study
Routine use of fibrinolytic therapy in all patients with prolonged CPR cannot therefore be recommended.
Weight and Patients’ Decision to Undergo Cardiac Surgery
Obese patients are less likely to have cardiac surgery than normal weight patients.
Optimization of Thromboelastography-Guided Platelet Transfusion in Cardiovascular Surgery
Use of a TEG-guided transfusion protocol dramatically reduced PT after CPB, particularly in patients undergoing aortic arch aneurysm repair.
Platelet Mapping as Part of Modified Thromboelastography (TEG®) in Patients Undergoing Cardiac Surgery and Cardiopulmonary Bypass
The platelet-mapping assay of the thromboelastograph was used to measure platelet aggregation and to examine the effect of cardiopulmonary bypass on multiple platelet receptors and the role of altered receptor activity in postoperative bleeding.
Efficacy of Tranexamic Acid in Paediatric Cardiac Surgery: A Systematic Review and Meta-Analysis
Evidence supporting the routine use of TXA in paediatric cardiac surgery remains weak.
How Do We Integrate Thromboelastography with Perioperative Transfusion Management?
In summary, we have found TEG to be useful in a variety of perioperative situations at our institution and potentially useful in other acute care settings such as the emergency department, the maternity unit, and many of the intensive care units.