Sustained Heparin Effect Contributes to Reduced Plasma Thrombin Generation Capacity Early after Cardiac Surgery
A marked reduction in thrombin generation potential was observed in the early postoperative phase after cardiac surgery.
Effect of a Single Bolus of Methylene Blue Prophylaxis on Vasopressor and Transfusion Requirement in Infective Endocarditis Patients Undergoing Cardiac Surgery
We aimed to evaluate the effect of prophylactic MB administration before CPB on vasopressor and transfusion requirements in patients with IE undergoing valvular heart surgery (VHS).
Prohemostatic Treatment in Cardiac Surgery
This article will discuss pharmacological agents including antifibrinolytics, protamine, desmopressin, fibrinogen, purified protein concentrates, recombinant factor VIIa, factor XIII, and topical agents used in cardiac surgery.
Protecting the Infant Brain During Cardiac Surgery: A Systematic Review
Prevention of brain injury during congenital heart surgery has focused on intraoperative and perioperative neuroprotection and neuromonitoring.
Aprotinin Revisited
The present review revisits the aprotinin controversy.
Pharmacokinetics of Tranexamic Acid in Patients Undergoing Cardiac Surgery with Use of Cardiopulmonary Bypass
We conducted a study to assess pharmacokinetics of high-dose tranexamic acid for 24 h after administration of the drug in patients undergoing cardiac surgery with cardiopulmonary bypass.
The Role of the VAD Perfusionist (EP Video)
Christopher Pierce discusses the new role of the VAD perfusionist (26:28 minutes).
Acute Massive Pulmonary Embolism and Hemodynamic Collapse in an 11 Week Post Cesarean Section Patient (EP Video)
Jenna Cornibe presents a case report on a patient 11 Week post cesarean section patient with a pulmonary embolism (27:54 minutes).
The Effect of Salvaged Blood on Coagulation Function as Measured by Thromboelastography
There is concern that salvaged blood has the potential to activate the coagulation system, which might place patients at risk of thrombotic complications.
Risks of Harms Using Antifibrinolytics in Cardiac Surgery: Systematic Review and Network Meta-Analysis of Randomised and Observational Studies
Although meta-analyses of randomised controlled trials were largely inconclusive, inclusion of observational data suggest concerns remain about the safety of aprotinin.
Red Blood Cell Transfusion: A Clinical Practice Guideline from the AABB
The AABB (formerly, the American Association of Blood Banks) developed this guideline to provide clinical recommendations about hemoglobin concentration thresholds and other clinical variables that trigger RBC transfusions in hemodynamically stable adults and children.
Venovenous Extracorporeal Membrane Oxygenation for Acute Lung Failure in Adults
Modern vv-ECMO is an excellent treatment in patients with severe ALF and should be more liberally used.