Antegrade Cerebral Perfusion Reduces Apoptotic Neuronal Injury in a Neonatal Piglet Model of Cardiopulmonary Bypass
We sought to evaluate and compare the extent of neurologic injury in a neonatal piglet model of deep hypothermic circulatory arrest and antegrade cerebral perfusion.
Lower Limits of Hematocrit and Mixed Venous Oxygen Saturation Ensuring Sufficient Cerebral Oxygenation During Hemodilution in Rabbits
This study was performed to identify critical values for these variables that would be able to ensure sufficient jugular venous oxygen saturation (SjO2), which reflects global cerebral oxygenation.
Low-Flow Perfusion Via the Innominate Artery During Aortic Arch Operations Provides Only Limited Somatic Circulatory Support
Aortic arch operations in pediatric patients using low-flow perfusion techniques have been standardized to a certain degree, but some of the often-stated beneficial effects have never been proven. Especially, the existence or efficacy of any subdiaphragmal perfusion still remains unclear.
Feasibility and Safety of Delivering Xenon to Patients Undergoing Coronary Artery Bypass Graft Surgery While on Cardiopulmonary Bypass: Phase I Study
Background: Postoperative neurocognitive deficit is prevalent after cardiac surgery. Xenon may prevent or ameliorate acute neuronal injury, but it also may aggravate injury […]
New Technology Feature: The LIFEBRIDGE B2T® Compact Heart-Lung System
The LIFEBRIDGE B2T® ("Bridge to Therapy") is a miniaturized and compact heart-lung support system.
New Technology Feature: The LIFEBRIDGE B2T® Compact Heart-Lung System
The LIFEBRIDGE B2T® ("Bridge to Therapy") is a miniaturized and compact heart-lung support system.
Improved Hemodynamics and Outcome After Modified Norwood Operation on the Beating Heart
This study compares postoperative hemodynamics and survival in patients who underwent Norwood procedure on the beating heart to those operated on with cardioplegic cardiac arrest.
Lung Perfusion With Clarithromycin Ameliorates Lung Function After Cardiopulmonary Bypass
Our study observed the protective effect of clarithromycin on inflammatory lung injury after cardiopulmonary bypass.
Phosphorylcholine Coating May Limit Thrombin Formation During High-Risk Cardiac Surgery: A Randomized Controlled Trial
We evaluated the effects of a Pc-coated oxygenator on blood coagulation in patients undergoing high-risk open heart surgery and receiving tranexamic acid.
International Perfusion Journal Vol. 2 No. 2
Table of Contents /Vol. 2, No. 2 Aprotinin Update: NEJM Vol. 354, No. 4, pp. 353 2006 Mangano, Tudor and Dietzel Kelly Hedlund […]
Coagulation Factor XIII Reduces Postoperative Bleeding After Coronary Surgery with Extracorporeal Circulation
In a prospective, randomized, double blinded study, 2500 units, 1250 units, and a placebo were administered in groups of 25 patients each, immediately after administration of protamine. Postoperative amount of blood loss and blood transfusion was recorded.
FDA Issues Public Health Advisory for Trasylol (Full Summary)
The Food and Drug Administration today issued a Public Health Advisory alerting doctors who perform heart bypass surgery, and their patients, that Trasyolol (aprotinin injection), a drug used to prevent blood loss during surgery, has been linked in two scientific publications to higher risks of serious side effects including kidney problems, heart attacks and strokes in patients who undergo artery bypass graft surgery.