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Signaling Effectors Underlying Pathologic Growth and Remodeling of the Heart
Cardiac hypertrophy is the strongest predictor for the development of heart failure, arrhythmia, and sudden death. Here we discuss therapeutic avenues emerging from molecular and genetic studies of cardiovascular disease in animal models.
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Cerebral Activation of Mitogen-Activated Protein Kinases After Circulatory Arrest and Low Flow Cardiopulmonary Bypass
Our results indicate that phosphorylated extracellular regulated kinase 1/2 may play a prominent role in early cerebral ischemia-reperfusion injury and endothelial dysfunction.
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Acute Biventricular Mechanical Circulatory Support for Cardiogenic Shock
The aim of this study was to explore the clinical utility of percutaneously delivered BiPella as a novel acute mechanical support strategy for patients with cardiogenic shock complicated by biventricular failure.
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