Population Pharmacokinetics of Olprinone in Patients Undergoing Cardiac Surgery with Cardiopulmonary Bypass
Therefore, the purpose of this study was to determine olprinone pharmacokinetic parameters in a large population undergoing cardiac surgery with CPB.
Alloimmunosensitization in Left Ventricular Assist Device Recipients and Impact on Posttransplantation Outcome
Despite the clinical success of these devices, it has been reported that many patients bridged to transplantation with mechanical support develop circulating antibodies with potential donor reactivity.
Cerebral Protection during Controlled Hypoperfusion in a Piglet Model: Comparison of Moderate (25°C) versus Deep (18°C) Hypothermia at Various Flow Rates Using Intraoperative Measurements and Ex Vivo Investigation
The aim of this study was to evaluate the effectiveness and safety of controlled cerebral hypoperfusion at moderate (25°C) versus deep (18°C) hypothermia.
Central Venous Oxygen Saturation During Cardiopulmonary Bypass Predicts 3-Year Survival
The present report explores the connection between SvO2 during cardiopulmonary bypass (CPB) and survival after cardiac surgery.
Intraoperative High-Dose Dexamethasone for Cardiac Surgery: A Randomized Controlled Trial
In our trial of adults undergoing cardiac surgery, the use of intraoperative dexamethasone did not reduce the 30-day incidence of major adverse events compared with placebo.
Cerebral Oximetry : Clinical Importance for Cardiac Surgery Patients
This suggests that cerebral oximetry is not only useful for neurological but also for hemodynamic monitoring and preoperative risk stratification of cardiac surgery patients.
Plutonium-238: An Ideal Power Source for Intracorporeal Ventricular Assist Devices?
Ventricular assist devices emerged as a widely used modality for treatment of end-stage heart failure; however, despite significant advances, external energy supply remains a problem contributing to significant patient morbidity and potential mortality.
A Recipe for Perioperative Cardioprotection: What Matters Most? The Ingredients or the Chef?
The question of what is the ideal anesthetic for patients with cardiovascular disease has been debated for nearly three decades, and similarly to the case for the use of perioperative beta blockers, the answer appears to be increasingly enigmatic.
Development of a New Arterial Line Filter Design Using Computational Fluid Dynamics Analysis
This article reviews theoretical principles of micropore filter technology and outlines the development of a new arterial-line filter concept using computational fluid dynamics analysis.
Ventricular Assist Device Malfunction: Sometimes It Is a Zebra
Preventing, recognizing, and troubleshooting problems with the many intricate systems used by perfusionists are key skills within the profession.
Our Experience with Two Cardioplegic Solutions: Dextrose versus Non-Dextrose in Adult Cardiac Surgery
Intraoperative hyperglycemia has been observed to be associated with increased morbidity and mortality after cardiac surgery. Dextrose cardioplegia is used for its cardioprotective effects but may lead to intraoperative hyperglycemia and more postoperative complications.
Validation of a Perfusion Registry: Methodological Approach and Initial Findings
Although regional and national registries exist to measure and report performance of cardiac surgical programs, few registries exist dedicated to the practice of cardiopulmonary bypass (CPB). We developed and implemented a cardiovascular perfusion registry (Perfusion Measures and outcomes [PERForm] Registry) within the structure of the Michigan Society of Thoracic and Cardiovascular Surgeons (MSTCVS) to improve our understanding of the practice of CPB.