Short-Acting P2Y12 Blockade to Reduce Platelet Dysfunction and Coagulopathy During Experimental Extracorporeal Circulation and Hypothermia
This experimental study tested P(2)Y(12) receptor blockade as an approach to protect platelets during ECC.
Low-Flow Antegrade Cerebral Perfusion Attenuates Early Renal and Intestinal Injury During Neonatal Aortic Arch Reconstruction
These results substantiate earlier suggestions that ACP provides more abdominal organ protection than DHCA in neonates undergoing aortic arch reconstruction.
Cold Reperfusion Before Rewarming Reduces Neurological Events after Deep Hypothermic Circulatory Arrest
Before rewarming, a 10-min period of cold perfusion significantly reduces incidence of NE.
Non-Invasive Estimation of Jugular Venous Oxygen Saturation: A Comparison Between Near Infrared Spectroscopy and Transcutaneous Venous Oximetry
Placement of cerebral oximetry patches directly over the internal jugular vein (as opposed to on the forehead) appeared to approximate internal jugular venous saturation better...
A Modified Protocol for Retrograde Cerebral Perfusion: Magnetic Resonance Spectroscopy in Pigs
Application of the modified RCP protocol significantly improved cerebral energy conservation during HCA and accelerated energy recovery after rewarming.
Is it Worth Packing the Head with Ice in Patients Undergoing Deep Hypothermic Circulatory Arrest?
We conclude that topical head cooling with ice is of use during DHCA but not during rewarming following DHCA and that it may be possible to advance topical head cooling techniques using circulating water rather than packed ice.
The Optimal Flow Rate for Antegrade Cerebral Perfusion During Deep Hypothermic Circulatory Arrest
Cerebral protection effects of ACP at 25 and 50 mL/kg/min were superior to that of ACP at 80 mL/kg/min as determined by cerebral markers, immunology, and histology.
Clinical Efficacy of Intermittent Pressure Augmented-Retrograde Cerebral Perfusion
IPA-RCP might provide more homogenous cerebral perfusion and a more effective oxygen supply to the brain with better clinical results than conventional RCP.
The Effects of Sevoflurane Anesthesia and Cardiopulmonary Bypass on Renal Function in Cyanotic and Acyanotic Children Undergoing Cardiac Surgery
We have concluded that renal function was not affected during open heart surgery with sevoflurane anesthesia, in both cyanotic and acyanotic children.
Establishment of a Co-Culture Model for Studying Inflammation after Pediatric Cardiopulmonary Bypass: From Bench to Bedside
Our coculture model could be useful for studies on the mechanisms of CPB-induced inflammation.
Surgical Management by Means of Electroretinographic Examination During Extracorporeal Circulation
This exam can assess the defect of the waves indicative of insufficient ocular and brain perfusion of patients supported by ECC during cardiosurgical interventions.
The Volatile Anesthetic Sevoflurane Inhibits Activation of Neutrophil Granulocytes During Simulated Extracorporeal Circulation
Sevoflurane inhibits granulocyte activation during ex vivo ECC and therefore has the potential to decrease the ECC-triggered inflammatory response.