Effects of Pre-Storage Leukoreduction on Stored Red Blood Cells Signaling: A Time-Course Evaluation from Shape to Proteome
The introduction of pre-storage leukoreduction in the preparation of standard RBCs intended for transfusion provided significant improvement in the quality of labile products and their post transfusion viability and effects, although the literature data are controversial.
ABO Incompatible Platelets: Risks versus Benefit
This review summarizes recent developments in the area of ABO compatibility and platelet transfusion and examines the risks and benefits associated with transfusion practices allowing for platelet ABO incompatibility.
Processed Residual Pump Blood in Cardiac Surgery: The Processed Residual Blood in Cardiac Surgery Trial
Ultrafiltration of residual CPB volume in adults undergoing isolated CABG surgery does not reduce the need for transfusion or bleeding.
Cytokine Phenotype, Genotype, and Renal Outcomes at Cardiac Surgery
Cytokine profiling may help predict early and late renal dysfunction.
Increased Risk of Acute Kidney Injury in Patients Undergoing Tricuspid Valve Surgery
We aimed to determine which patients undergoing tricuspid valve (TV) surgery are at increased risk for acute kidney injury (AKI).
Fresh and Stored Red Blood Cell Transfusion Equivalently Induce Subclinical Pulmonary Gas Exchange Deficit in Normal Humans
We tested the hypothesis that transfusion can cause mild pulmonary dysfunction that has not been noticed clinically and is not sufficiently severe to fit the definition of transfusion-related acute lung injury.
Cell-Derived Microparticles in Stored Blood Products: Innocent-Bystanders or Effective Mediators of Post-Transfusion Reactions?
Plasma membrane-derived microvesicles or microparticles (MPs) are sub-cellular vesicles released upon shear stress, cell activation, injury or apoptosis.
Acute Neurological Complications after Pediatric Cardiac Surgery: Still a Long Way to Go
Our incidence of neurological complications after cardiac surgery is similar to that previously described.
Effect of Processing and Storage on Red Blood Cell Function In Vivo
Red blood cell (RBC) transfusion is indicated to improve oxygen delivery to tissue, and for no other purpose.
Haemostatic Therapy in Coronary Artery Bypass Graft Patients with Decreased Platelet Function: Comparison of Fibrinogen Concentrate with Allogeneic Blood Products
Fibrinogen concentrate administration increased the fibrin clot quality and helped achieve haemostasis.
Effects of Magnesium Sulphate on Postoperative Coagulation, Measured by Rotational Thromboelastometry (ROTEM(®)).
Intra-operative infusion of magnesium sulphate seems to attenuate postoperative hypercoagulability by maintaining magnesium levels at the upper limit of the normal range.
Impact of Transfusion of Autologous 7- versus 42-Day-Old AS-3 Red Blood Cells on Tissue Oxygenation and the Microcirculation in Healthy Volunteers
Transfusion of 1 unit of 42-day-stored RBCs to healthy subjects has no overt detrimental effect on tissue oxygenation or the microcirculation assessed by clinically available monitors.