Preservation Solution Supplemented with Biliverdin Prevents Lung Cold Ischaemia/Reperfusion Injury
This study demonstrates that the exposure of the lung grafts to BV during cold storage can impart potent cytoprotective effects to lung cold ischaemia/reperfusion injury and significantly improve the lung graft function following extended cold preservation and transplantation by the mechanism of a reduction in oxidative injury and following inflammatory events.
Near-Infrared Spectroscopy Cerebral and Somatic (Renal) Oxygen Saturation Correlation to Continuous Venous Oxygen Saturation via Intravenous Oximetry Catheter
In this small cohort of pediatric patients undergoing heart surgery, there was a moderate but statistically significant correlation between the ScvO(2)-catheter and the NIRS-C values.
Changes in Microvascular Reactivity after Cardiopulmonary Bypass in Patients with Poorly Controlled versus Controlled Diabetes
Poorly controlled diabetes results in impaired arteriolar function before and after CPB.
Fluid Balance as an Early Indicator of Acute Kidney Injury in CV Surgery
We hypothesized that positive fluid balance (FB) is the result of intraoperative kidney injury and associated renal vasoconstriction, and therefore may be an early clinical indicator of acute kidney injury (AKI).
What Blood Temperature for an Ex Vivo Extracorporeal Circuit?
Investigators in this field must be aware of the fact that blood temperature is a crucial confounding parameter and the type of "background noise" they will face depending on the strategy adopted.
Use of Prothrombin Complex Concentrate for Excessive Bleeding after Cardiac Surgery
Administration of low-dose of PCC significantly decreased postoperative bleeding after CPB.
Usefulness of Postoperative Atrial Fibrillation as an Independent Predictor for Worse Early and Late Outcomes after Isolated Coronary Artery Bypass Grafting (Multicenter Australian Study of 19,497 Patients)
POAF is a risk factor for short-term morbidity and decreased long-term survival.
Air Embolism During Off-Pump Coronary Artery Bypass Graft Surgery -A Case Report-
In this report, we describe a rare case of air embolism in the coronary arteries associated with the use of a CO(2) blower during OPCAB.
Risk Factors for Conversion to Cardiopulmonary Bypass During Off-Pump Coronary Artery Bypass Surgery
Conversion to cardiopulmonary bypass during OPCAB is associated with increased in-hospital and long-term mortality and may be related to surgeon experience.
The Age of Blood Evaluation (ABLE) Randomized Controlled Trial: Study Design
The "Age of Blood Evaluation" (ABLE) study (ISRCTN44878718) is a double-blind, multicenter, parallel randomized controlled clinical trial.
Longer Blood Storage is Associated with Suboptimal Outcomes in High-Risk Pediatric Cardiac Surgery
The freshest RBC units available should be used for pediatric cardiac operations expected to require more than 4 units or more than 150 mL/kg of allogeneic RBC transfusions, with no units more than 14 days old being transfused whenever possible.
Effects of Pre-Storage Leukoreduction on Stored Red Blood Cells Signaling: A Time-Course Evaluation from Shape to Proteome
The introduction of pre-storage leukoreduction in the preparation of standard RBCs intended for transfusion provided significant improvement in the quality of labile products and their post transfusion viability and effects, although the literature data are controversial.