Transfusion Immunomodulation – The Case for Leukoreduced and (Perhaps) Washed Transfusions
The present review will focus on two approaches, leukoreduction and saline washing, as means to reduce adverse transfusion outcomes.
Prospective Validation of the Vasoactive-Inotropic Score and Correlation to Short-Term Outcomes in Neonates and Infants after Cardiothoracic Surgery
In neonates and infants, a higher VIS at 48 h after cardiothoracic surgery is strongly associated with increased length of ventilation, and prolonged ICU and total hospital stay.
A Pilot Feasibility Trial of Allocation of Freshest Available Red Blood Cells versus Standard Care in Critically Ill Patients
We aimed to evaluate in intensive care unit (ICU) patients 1) the feasibility of allocating freshest available compatible RBCs versus standard care and 2) the suitability of this approach in the design of a large randomized controlled trial (RCT).
ABO Incompatible Platelets: Risks versus Benefit
This review summarizes recent developments in the area of ABO compatibility and platelet transfusion and examines the risks and benefits associated with transfusion practices allowing for platelet ABO incompatibility.
Air Embolism During Off-Pump Coronary Artery Bypass Graft Surgery -A Case Report-
In this report, we describe a rare case of air embolism in the coronary arteries associated with the use of a CO(2) blower during OPCAB.
Changes in Microvascular Reactivity after Cardiopulmonary Bypass in Patients with Poorly Controlled versus Controlled Diabetes
Poorly controlled diabetes results in impaired arteriolar function before and after CPB.
Effect of Fresh Red Blood Cell Transfusions on Clinical Outcomes in Premature, Very Low-Birth-Weight Infants: The ARIPI Randomized Trial
In this trial, the use of fresh RBCs compared with standard blood bank practice did not improve outcomes in premature, very low-birth-weight infants requiring a transfusion.
Transfusion Thresholds and other Strategies for Guiding Allogeneic Red Blood Cell Transfusion
The purpose of this review is to compare clinical outcomes in patients randomised to restrictive versus liberal transfusion thresholds (triggers).
Prolonged Central Venous Desaturation Measured by Continuous Oximetry is Associated with Adverse Outcomes in Pediatric Cardiac Surgery
We demonstrate that ScvO₂ desaturations by continuous oximetry are associated with major adverse events in pediatric patients undergoing cardiac surgery.
Fibrinogen Function is Impaired in Whole Blood from Patients with Cyanotic Congenital Heart Disease
Patients with CCHD are hypocoagulable mainly due to impaired fibrinogen function.
Preservation Solution Supplemented with Biliverdin Prevents Lung Cold Ischaemia/Reperfusion Injury
This study demonstrates that the exposure of the lung grafts to BV during cold storage can impart potent cytoprotective effects to lung cold ischaemia/reperfusion injury and significantly improve the lung graft function following extended cold preservation and transplantation by the mechanism of a reduction in oxidative injury and following inflammatory events.
Increased Risk of Acute Kidney Injury in Patients Undergoing Tricuspid Valve Surgery
We aimed to determine which patients undergoing tricuspid valve (TV) surgery are at increased risk for acute kidney injury (AKI).