Perioperative Red Blood Cell Transfusion: Harmful or Beneficial to the Patient?
This review focuses on the physiology of oxygen transport, the hazards of acute anemia, the hazards of RBC transfusion, and the literature putting these problems into perspective.
Early Platelet Dysfunction: An Unrecognized Role in the Acute Coagulopathy of Trauma
In this study, we show that platelet dysfunction is manifest after major trauma and before substantial fluid or blood administration.
Effect of a Single Bolus of Methylene Blue Prophylaxis on Vasopressor and Transfusion Requirement in Infective Endocarditis Patients Undergoing Cardiac Surgery
We aimed to evaluate the effect of prophylactic MB administration before CPB on vasopressor and transfusion requirements in patients with IE undergoing valvular heart surgery (VHS).
How Do We Integrate Thromboelastography with Perioperative Transfusion Management?
In summary, we have found TEG to be useful in a variety of perioperative situations at our institution and potentially useful in other acute care settings such as the emergency department, the maternity unit, and many of the intensive care units.
Reoperation for Bleeding in Cardiac Surgery
To reduce the rate of reoperations and mortality due to postoperative bleeding, we aim to identify risk factors that predict reoperation.
Is There a Suitable Method of Anticoagulation in Pregnant Patients with Mechanical Prosthetic Heart Valves?
A best evidence topic was written according to a structured protocol in order to identify the mode of anticoagulation that has the best safety profile for both the mother and the foetus in pregnant patients with mechanical prosthetic heart valves.
Platelet-Dependent Thrombography Gives a Distinct Pattern of In Vitro Thrombin Generation after Surgery with Cardio-Pulmonary Bypass: Potential Implications
Our results show that experimental conditions have a profound effect in the study of in vitro thrombin generation in the context of CPB.
Platelet Mapping as Part of Modified Thromboelastography (TEG®) in Patients Undergoing Cardiac Surgery and Cardiopulmonary Bypass
The platelet-mapping assay of the thromboelastograph was used to measure platelet aggregation and to examine the effect of cardiopulmonary bypass on multiple platelet receptors and the role of altered receptor activity in postoperative bleeding.
Sustained Heparin Effect Contributes to Reduced Plasma Thrombin Generation Capacity Early after Cardiac Surgery
A marked reduction in thrombin generation potential was observed in the early postoperative phase after cardiac surgery.
Efficacy of Tranexamic Acid in Paediatric Cardiac Surgery: A Systematic Review and Meta-Analysis
Evidence supporting the routine use of TXA in paediatric cardiac surgery remains weak.