Preservation Solution Supplemented with Biliverdin Prevents Lung Cold Ischaemia/Reperfusion Injury
This study demonstrates that the exposure of the lung grafts to BV during cold storage can impart potent cytoprotective effects to lung cold ischaemia/reperfusion injury and significantly improve the lung graft function following extended cold preservation and transplantation by the mechanism of a reduction in oxidative injury and following inflammatory events.
Increased Risk of Acute Kidney Injury in Patients Undergoing Tricuspid Valve Surgery
We aimed to determine which patients undergoing tricuspid valve (TV) surgery are at increased risk for acute kidney injury (AKI).
Insufflation of Hydrogen Gas Restrains the Inflammatory Response of Cardiopulmonary Bypass in a Rat Model
We suggest that H(2) insufflation is a possible new potential therapy for counteracting CPB-induced systemic inflammation.
Acute Hyponatremia after Cardioplegia by Histidine-Tryptophane-Ketoglutarate–A Retrospective Study
Acute hyponatremia during cardioplegia with HTK solution is isotonic and should probably not be corrected without presence of hypotonicity as confirmed by measurement of serum osmolality.
Advances in Mechanical Circulatory Support in the Treatment of Heart Failure
In recent years, the implantation of Ventricular Assist Devices (VAD) as definitive therapy (DT) has emerged as a promising replacement therapy for heart transplantation.
The Pharmacotherapy Implications of Ventricular Assist Device in the Patient with End-Stage Heart Failure
A basic understanding of this unique therapy can assist pharmacists in attending to the needs of patients with VAD.
Anticoagulation and Bleeding in Patients with Ventricular Assist Devices: Walking the Tightrope
A left ventricular assist device (LVAD) is a lifesaving therapy for end-stage heart failure, but it is associated with major complications such as bleeding and thrombosis.
Pulsatile Control of Rotary Blood Pumps: Does the Modulation Waveform Matter?
A synchronized pulsing rotary blood pump offers a simple and powerful control modality for heart unloading.
Performance Evaluation of a Pediatric Viscous Impeller Pump for Fontan Cavopulmonary Assist
A VIP will augment Fontan cavopulmonary flow in the proper pressure and flow ranges, with low hemolysis risk under more stringent pediatric scale and physiology compared with adult scale.
Cost-Effectiveness of the Implantable HeartMate II Left Ventricular Assist Device for Patients Awaiting Heart Transplantation
Although HeartMate II LVAD implantation significantly increases survival compared with conventional medical management, it does not provide good value for the money spent according to established thresholds of cost-effectiveness in the UK.
Hydrogen as Additive of HTK Solution Fortifies Myocardial Preservation in Grafts with Prolonged Cold Ischemia
Hydrogen as additive of HTK solution fortifies HTK's preservation efficacy for cardiac grafts subjected to prolonged cold ischemia by inhibiting cold ischemia-induced up-regulation of oxidative stress, inflammation mediators, and apoptosis.
Preservation of Myocardium During Coronary Artery Bypass Surgery
In the present review article on myocardial protection in contemporary coronary artery bypass surgery, we attempt to elucidate the clinical problems, summarize the outcomes of selected phase III trials, and introduce new perspectives.