Peroperative Effects of Fresh Frozen Plasma and Antithrombin III on Heparin Sensitivity and Coagulation during Nitroglycerine Infusion in Coronary Artery Bypass Surgery
ATIII may be preferred to FFP in patients with heparin resistance due to NTG infusion undergoing CABGS.
Risk Factors for Conversion to Cardiopulmonary Bypass During Off-Pump Coronary Artery Bypass Surgery
Conversion to cardiopulmonary bypass during OPCAB is associated with increased in-hospital and long-term mortality and may be related to surgeon experience.
Cytokine Phenotype, Genotype, and Renal Outcomes at Cardiac Surgery
Cytokine profiling may help predict early and late renal dysfunction.
Haemostatic Therapy in Coronary Artery Bypass Graft Patients with Decreased Platelet Function: Comparison of Fibrinogen Concentrate with Allogeneic Blood Products
Fibrinogen concentrate administration increased the fibrin clot quality and helped achieve haemostasis.
Selective Pulmonary Pulsatile Perfusion with Oxygenated Blood During Cardiopulmonary Bypass Attenuates Lung Tissue Inflammation but Does Not Affect Circulating Cytokine Levels
Improved respiratory outcome has been shown after selective pulsatile pulmonary perfusion (sPPP) during cardiopulmonary bypass (CPB).
Fresh Red Blood Cell Transfusion and Short-Term Pulmonary, Immunologic, and Coagulation Status: A Randomized Clinical Trial
In this randomized clinical trial, no differences were noted in early measures of pulmonary function or in immunologic or coagulation status when comparing fresh versus standard issue single-unit RBC transfusion.
Effects of Magnesium Sulphate on Postoperative Coagulation, Measured by Rotational Thromboelastometry (ROTEM(®)).
Intra-operative infusion of magnesium sulphate seems to attenuate postoperative hypercoagulability by maintaining magnesium levels at the upper limit of the normal range.
The Efficacy of Parecoxib on Systemic Inflammatory Response Associated with Cardiopulmonary Bypass During Cardiac Surgery
Intraoperative parecoxib attenuated systemic inflammatory response associated with CPB during cardiac surgery and lowered the biochemical markers of myocardial injury.
Cerebral and Somatic Near-Infrared Spectroscopy Measurements During Fluid Challenge in Cardiac Surgery Patients: A Descriptive Pilot Study
Little is known about changes in near-infrared spectroscopy (NIRS)-derived cerebral (rSO(2)b) and somatic (rSO(2)s) oxygen saturation during a fluid challenge.
Fibrinogen Function is Impaired in Whole Blood from Patients with Cyanotic Congenital Heart Disease
Patients with CCHD are hypocoagulable mainly due to impaired fibrinogen function.
The Influence of Heparin Resistance on Postoperative Complications in Patients Undergoing Coronary Surgery
Severe form of heparin resistance (expressed by the ACT less than 480 seconds after 400 U/kg heparin) was an independent predictor of death.
The Age of Blood Evaluation (ABLE) Randomized Controlled Trial: Study Design
The "Age of Blood Evaluation" (ABLE) study (ISRCTN44878718) is a double-blind, multicenter, parallel randomized controlled clinical trial.