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Association of Heparin Dose, Route, Timing, and Duration With Heparin-Induced Thrombocytopenia
Odds of HIT were increased 10-fold in adult cardiac surgery patients receiving preoperative or postoperative intravenous UFH infusion. Intraoperative UFH dose and subcutaneous route were not associated with HIT. Future study should evaluate incorporation of intravenous UFH administration, dose, and duration in HIT scoring tools for cardiac surgery patients.
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Mild Hypothermia During Prolonged Cardiopulmonary Cerebral Resuscitation Increases Conscious Survival in Dogs
Mild or moderate hypothermia during prolonged CPCR in dogs preserves viability of extracerebral organs and improves outcome.
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In Vivo Protamine Titration Using Activated Coagulation Time to Neutralize Heparin Anticoagulation in Cardiac Surgery: Proof of Concept
The aim of the present study was to determine the optimal protamine/heparin ratio to reverse anticoagulation using IVPT curves.
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