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Intraoperative Mechanical Ventilation And Postoperative Pulmonary Complications After Cardiac Surgery
In this retrospective analysis, the intraoperative ventilation bundle was associated with a lower rate of postoperative pulmonary complicationsLower modified driving pressure was independently associated with fewer pulmonary complications BACKGROUND:: Compared with historic ventilation strategies, modern lung-protective ventilation includes lower tidal volumes (VT), lower driving pressures, and application of positive end-expiratory pressure (PEEP). The contributions of each component to an overall intraoperative protective ventilation strategy aimed at reducing postoperative pulmonary complications have neither been adequately resolved, nor comprehensively evaluated within an adult cardiac surgical population.
Influence of Cardiopulmonary Bypass on the Interaction of Recombinant Factor VIIa with Activated Platelets
Recombinant factor VIIa (rFVIIa) interacts preferentially with coated platelets characterized by a high exposure of phosphatidyl serine (PS), FV, FVIII, FIX, and FX binding, and fibrinogen.
Hereditary Antithrombin Deficiency (EP Video)
Barry Fry discusses the role of Thrombate III in hereditary antithrombin deficiency (10:13 minutes).
