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Methylprednisolone Plasma Concentrations During Cardiac Surgery With Cardiopulmonary Bypass in Pediatric Patients
We report similar methylprednisolone plasma concentrations as earlier studies performed in children undergoing cardiopulmonary bypass, and we confirmed the large interindividual variability in achieved methylprednisolone plasma concentrations with weight-based methylprednisolone administration. A larger volume of distribution and a lower clearance of methylprednisolone for neonates were suggested. The half-life of methylprednisolone in our study was calculated to be longer than 6 h for neonates, 4.7 h for infants, 3.6 h for preschool children and 4.7 h for school children. The possible influence of treatment of pulmonary hypertension with sildenafil and temperature needs to be investigated further.
Advocacy Group Sues FDA, Claims Agency is Withholding Risks of Xenotransplantation
WASHINGTON (Reuters Health) – The Campaign for Responsible Transplantation (CRT) on Monday has asked a federal district court to compel the US […]
‘Surfers Time Line- Though the Last 9 Years :)
Editor’s Note: I thought I would put together a thumbnail gallery of the life and times @ Circuit Surfers, as a way […]