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Saudi Guidelines on the Diagnosis and Treatment of Pulmonary Hypertension: Chronic Thromboembolic Pulmonary Hypertension
In this review, we provide a detailed discussion on diagnostic algorithm, surgical operability criteria, pulmonary endarterectomy (PEA), and the medical therapy.
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Degradation of the Endothelial Glycocalyx Contributes to Metabolic Acidosis in Children Following Cardiopulmonary Bypass Surgery
Our data show that metabolic acidosis (increased strong ion gap) is associated with plasma concentration of heparan sulfate, a negatively charged glycosaminoglycan cleaved from the endothelial glycocalyx during cardiopulmonary bypass. In addition, cleavage of heparan sulfate was associated with renal dysfunction, capillary leak, and global markers of cardiovascular dysfunction. These data highlight the importance of designing translational therapies to protect the glycocalyx in cardiopulmonary bypass.
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Extracorporeal Membrane Oxygenation in Pediatric Patients: Our Experience in the Last Ten Years
The use of extracorporeal membrane oxygenation (ECMO) in children after cardiac surgery is well established. ECMO support is becoming an integral tool for cardiopulmonary resuscitation in specified centers.
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