COVID-19 Pneumonia: ARDS or Not?
We propose the presence of two types of patients (“non-ARDS,” type 1, and ARDS, type 2) with different pathophysiology.
Medically-Necessary, Time-Sensitive Procedures: A Scoring System to Ethically and Efficiently Manage Resource Scarcity and Provider Risk During the COVID-19 Pandemic
This approach is applicable across a broad range of hospital settings (academic and community, urban and rural) in the midst of the pandemic and may be able to inform case triage as OR capacity resumes once the acute phase of the pandemic subsides.
Looking to the Future to Prepare for Covid-19’s Second Wave
Ewelina Biskup, MD, MPH, calls for robust data recording and the creation of a big data set to support analysis to improve care for the next waves.
COVID-19 Pneumonia: Different Respiratory Treatments for Different Phenotypes?
Understanding the correct pathophysiology is crucial to establishing the basis for appropriate treatment.
The Procoagulant Pattern of Patients with COVID‐19 Acute Respiratory Distress Syndrome
The pro‐coagulant pattern of these patients may justify the clinical reports of thromboembolic complications (pulmonary embolism) during the course of the disease. Further studies are needed to assess the best prophylaxis and treatment of this condition.
Microvascular COVID-19 Lung Vessels Obstructive Thromboinflammatory Syndrome (MicroCLOTS): an Atypical Acute Respiratory Distress Syndrome Working Hypothesis
We suggest the use of MicroCLOTS (microvascular COVID-19 lung vessels obstructive thromboinflammatory syndrome) as a new name for severe pulmonary coronavirus disease 2019 (COVID-19).
Neurologic Features in Severe SARS-CoV-2 Infection
In this consecutive series of patients, ARDS due to SARS-CoV-2 infection was associated with encephalopathy, prominent agitation and confusion, and corticospinal tract signs.
Clinical Impact of Massive Transfusion Protocol Implementation in Non-Traumatic Patients
MTP implementation showed improved coagulation profiles, but did not show a statistically significant death-rate reduction in non-traumatic patients.
Comparison of Hemoglobin and Hematocrit Levels at 1, 4 and 24 h after Red Blood Cell Transfusion
The equilibration of Hb and Hct did not differ between one, four and 24 h after a RBC transfusion.
Prolonged Cardiopulmonary Bypass is Associated With Endothelial Glycocalyx Degradation
Development of therapy targeting EG shedding may be beneficial in patients with prolonged CPB.
Decreased Mean Perfusion Pressure as an Independent Predictor of Acute Kidney Injury after Cardiac Surgery
The duration of differences in perfusion pressure to the kidneys during CPB compared to baseline is an independent predictor of AKICS.
Association between Cerebral Oxygen Saturation with Outcome in Cardiac Surgery: Brain as an Index Organ
In cardiac surgical patients who received interventions to correct decreases in rSO2, increased severity of intraoperative decrease in rSO2 as reflected by AUT below an absolute value of 50% was associated with a composite of adverse outcomes, implicating the importance of cerebral oximetry to monitor the brain as an index organ.