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Utility of Thromboelastography versus Routine Coagulation Tests for Assessment of Hypocoagulable State in Patients Undergoing Cardiac Bypass Surgery
This study was done to evaluate usefulness of Thromboelastography (TEG) and routine coagulation tests (RCT) in assessing hemostatic changes and predicting postoperative bleeding in patients undergoing cardiac surgery with cardiopulmonary bypass.
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Toll-like Receptor 9 and the Inflammatory Response to Surgical Trauma and Cardiopulmonary Bypass
CPB, surgical trauma and ischemic perfusion injury trigger the release of circulating mtDNA that activates TLR-9, in turn stimulating a release of IL-6. Therefore, TLR-9 antagonists may attenuate this response and may provide a future therapeutic target whereby the systemic inflammatory response to cardiac surgery may be manipulated to improve clinical outcomes.
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Early Use of Hemoadsorption in Patients after Out-Of Hospital Cardiac Arrest – A Matched Pair Analysis
Routine use of hemoadsorption did not reduce, but seems to be associated with higher 30-day mortality in patients after OHCA.
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