Microvascular COVID-19 Lung Vessels Obstructive Thromboinflammatory Syndrome (MicroCLOTS): an Atypical Acute Respiratory Distress Syndrome Working Hypothesis

Innate Immune Activation after Transfusion of Stored Red Blood Cells

In this narrative review, we explore the hypothesis that prolonged RBC storage results in elaboration of substances which may function as danger associated molecular pattern molecules that activate the innate immune system with consequences unfavorable to healthy homeostasis.