Protecting the Infant Brain During Cardiac Surgery: A Systematic Review
Prevention of brain injury during congenital heart surgery has focused on intraoperative and perioperative neuroprotection and neuromonitoring.
Aprotinin Revisited
The present review revisits the aprotinin controversy.
Pharmacokinetics of Tranexamic Acid in Patients Undergoing Cardiac Surgery with Use of Cardiopulmonary Bypass
We conducted a study to assess pharmacokinetics of high-dose tranexamic acid for 24 h after administration of the drug in patients undergoing cardiac surgery with cardiopulmonary bypass.
Perioperative Red Blood Cell Transfusion: Harmful or Beneficial to the Patient?
This review focuses on the physiology of oxygen transport, the hazards of acute anemia, the hazards of RBC transfusion, and the literature putting these problems into perspective.
Early Platelet Dysfunction: An Unrecognized Role in the Acute Coagulopathy of Trauma
In this study, we show that platelet dysfunction is manifest after major trauma and before substantial fluid or blood administration.
Analytical Performance Evaluation of Four Cartridge-Type Blood Gas Analyzers
Globally, all four cartridge-type blood gas analyzers produced clinically acceptable results.
The Role of the VAD Perfusionist (EP Video)
Christopher Pierce discusses the new role of the VAD perfusionist (26:28 minutes).
Acute Massive Pulmonary Embolism and Hemodynamic Collapse in an 11 Week Post Cesarean Section Patient (EP Video)
Jenna Cornibe presents a case report on a patient 11 Week post cesarean section patient with a pulmonary embolism (27:54 minutes).
Red Blood Cell Transfusion: A Clinical Practice Guideline from the AABB
The AABB (formerly, the American Association of Blood Banks) developed this guideline to provide clinical recommendations about hemoglobin concentration thresholds and other clinical variables that trigger RBC transfusions in hemodynamically stable adults and children.
The Effect of Salvaged Blood on Coagulation Function as Measured by Thromboelastography
There is concern that salvaged blood has the potential to activate the coagulation system, which might place patients at risk of thrombotic complications.
Risks of Harms Using Antifibrinolytics in Cardiac Surgery: Systematic Review and Network Meta-Analysis of Randomised and Observational Studies
Although meta-analyses of randomised controlled trials were largely inconclusive, inclusion of observational data suggest concerns remain about the safety of aprotinin.
Feasibility of Initiating Extracorporeal Life Support During Mechanical Chest Compression CPR: A Porcine Pilot Study
Mechanical chest compression may be a suitable therapeutic bridge to the installation of ECMO and does not interfere with ECMO catheter placement.