Sustained Heparin Effect Contributes to Reduced Plasma Thrombin Generation Capacity Early after Cardiac Surgery
A marked reduction in thrombin generation potential was observed in the early postoperative phase after cardiac surgery.
Efficacy of Tranexamic Acid in Paediatric Cardiac Surgery: A Systematic Review and Meta-Analysis
Evidence supporting the routine use of TXA in paediatric cardiac surgery remains weak.
Protecting the Infant Brain During Cardiac Surgery: A Systematic Review
Prevention of brain injury during congenital heart surgery has focused on intraoperative and perioperative neuroprotection and neuromonitoring.
Pharmacokinetics of Tranexamic Acid in Patients Undergoing Cardiac Surgery with Use of Cardiopulmonary Bypass
We conducted a study to assess pharmacokinetics of high-dose tranexamic acid for 24 h after administration of the drug in patients undergoing cardiac surgery with cardiopulmonary bypass.
Hyperfibrinolysis is Common in Out-of-Hospital Cardiac Arrest: Results from a Prospective Observational Thromboelastometry Study
Routine use of fibrinolytic therapy in all patients with prolonged CPR cannot therefore be recommended.
The Role of the VAD Perfusionist (EP Video)
Christopher Pierce discusses the new role of the VAD perfusionist (26:28 minutes).
Acute Massive Pulmonary Embolism and Hemodynamic Collapse in an 11 Week Post Cesarean Section Patient (EP Video)
Jenna Cornibe presents a case report on a patient 11 Week post cesarean section patient with a pulmonary embolism (27:54 minutes).
Antiplatelet Therapy in Patients with Coronary Artery Stents for Noncardiac Surgery: Role of Thromboelastography
The perioperative course of the patients who have undergone coronary stent placement was studied. These patients were on dual antiplatelet therapy and were posted for noncardiac surgery.
A Randomized Prospective Analysis of Alteration of Hemostatic Function in Patients Receiving Tranexamic Acid and Hydroxyethyl Starch Undergoing Off Pump Coronary Artery Bypass Surgery
Postoperative hemorrhagic complications is still one of the major problems in cardiac surgeries. It may be caused by surgical issues, coagulopathy caused by the side effects of the intravenous fluids administered to produce plasma volume expansion such as hydroxyl ethyl starch (HES).
Bivalirudin-Based Versus Conventional Heparin Anticoagulation for Postcardiotomy Extracorporeal Membrane Oxygenation
The present study is a retrospective comparison of the conventional heparin-based anticoagulation protocol with a bivalirudin-based, heparin-free protocol. Endpoints of this study are blood loss, allogeneic blood product use, and costs during the ECMO procedure.
A Method for Anticoagulation of Children on Mechanical Circulatory Support
We describe an anticoagulation protocol based upon TEG and platelet aggregation studies and using heparin, aspirin, and dipyridamole. Adequate anticoagulation is more difficult in children. However, 71% of the patients in our study survived long term.
Monitoring Patients at Risk of Massive Transfusion with Thrombelastography or Thromboelastometry: A Systematic Review
Thrombelastography (TEG) and Thrombelastometry (ROTEM) are viscoelastic whole-blood assays evaluating the haemostatic capacity of blood. These devices are used in algorithms to guide transfusion of haemostatic blood components.