Optimization of Leukocyte Concentration in Platelet-Rich Plasma for the Treatment of Tendinopathy
The optimum composition of PRP for the treatment of tendinopathy has not been directly investigated. Persistent inflammation results in inferior repair with scar tissue. The present study indicates that in an animal model, WBC in PRP contributes to inflammatory cytokine production. Therefore, leukocyte-reduced PRP may be the optimum preparation to stimulate superior healing without scar tissue formation.
Treatment of Athletic Tendonopathy
This article reviews the most widely used treatments for tendinopathy and outlines the literature support for their use.
Use of Autologous Fibrin Glue (Platelet-Poor Plasma) in Abdominal Dermolipectomies
The PPP fostered adhesion between the abdominal dermoadipose flap and the aponeurotic surface only on the first POD and had no influence whatsoever on the incidence of seroma. There are few reports on the use of PPP for plastic surgery, particularly the autologous type, opening up possibilities for further research projects to expand its use.
Autologous Platelet-Rich Plasma for Treating Chronic Wounds
Autologous platelet-rich plasma (PRP) is a treatment that contains fibrin and high concentrations of growth factors and has the potential to aid wound healing.
Preparation of Platelet-Rich Plasma from Small Volume of Whole Blood – A Simplified Approach
This study demonstrates a simple, rapid and inexpensive technique that is useful in obtaining platelets concentrated approximately 11-fold.
Red Blood Cell Transfusion: A Clinical Practice Guideline from the AABB
The AABB (formerly, the American Association of Blood Banks) developed this guideline to provide clinical recommendations about hemoglobin concentration thresholds and other clinical variables that trigger RBC transfusions in hemodynamically stable adults and children.
Risks of Harms Using Antifibrinolytics in Cardiac Surgery: Systematic Review and Network Meta-Analysis of Randomised and Observational Studies
Although meta-analyses of randomised controlled trials were largely inconclusive, inclusion of observational data suggest concerns remain about the safety of aprotinin.
The Effect of Salvaged Blood on Coagulation Function as Measured by Thromboelastography
There is concern that salvaged blood has the potential to activate the coagulation system, which might place patients at risk of thrombotic complications.
Leukocyte Filtration of Blood Cardioplegia Attenuates Myocardial Damage and Inflammation
cLkF during blood cardioplegia attenuates myocardial ischaemia/reperfusion injury and reduces perioperative leakage of TnI, lactate and pro-inflammatory cytokines.
Emergency Circulatory Support in Refractory Cardiogenic Shock Patients in Remote Institutions: A Pilot Study (The Cardiac-RESCUE Program).
Offering local ECMO support appears feasible in a majority of RCS patients hospitalized in remote hospitals.
The Role of Echocardiography in the Management of Patients Supported by Extracorporeal Membrane Oxygenation
Although there are extensive published data regarding ECMO, particularly in the pediatric population, there is a paucity of data outlining the role of echocardiography in guiding the management of adult patients supported by ECMO.
Feasibility of Initiating Extracorporeal Life Support During Mechanical Chest Compression CPR: A Porcine Pilot Study
Mechanical chest compression may be a suitable therapeutic bridge to the installation of ECMO and does not interfere with ECMO catheter placement.