Is There a Suitable Method of Anticoagulation in Pregnant Patients with Mechanical Prosthetic Heart Valves?
A best evidence topic was written according to a structured protocol in order to identify the mode of anticoagulation that has the best safety profile for both the mother and the foetus in pregnant patients with mechanical prosthetic heart valves.
Aprotinin Revisited
The present review revisits the aprotinin controversy.
Perioperative Red Blood Cell Transfusion: Harmful or Beneficial to the Patient?
This review focuses on the physiology of oxygen transport, the hazards of acute anemia, the hazards of RBC transfusion, and the literature putting these problems into perspective.
Platelet Mapping as Part of Modified Thromboelastography (TEG®) in Patients Undergoing Cardiac Surgery and Cardiopulmonary Bypass
The platelet-mapping assay of the thromboelastograph was used to measure platelet aggregation and to examine the effect of cardiopulmonary bypass on multiple platelet receptors and the role of altered receptor activity in postoperative bleeding.
An Original Model to Predict Intensive Care Unit Length-of Stay after Cardiac Surgery in a Competing Risk Framework
ICU-LOS can be predicted by preoperative data and type of surgeries.
Early Platelet Dysfunction: An Unrecognized Role in the Acute Coagulopathy of Trauma
In this study, we show that platelet dysfunction is manifest after major trauma and before substantial fluid or blood administration.
Platelet-Dependent Thrombography Gives a Distinct Pattern of In Vitro Thrombin Generation after Surgery with Cardio-Pulmonary Bypass: Potential Implications
Our results show that experimental conditions have a profound effect in the study of in vitro thrombin generation in the context of CPB.
Sustained Heparin Effect Contributes to Reduced Plasma Thrombin Generation Capacity Early after Cardiac Surgery
A marked reduction in thrombin generation potential was observed in the early postoperative phase after cardiac surgery.
Efficacy of Tranexamic Acid in Paediatric Cardiac Surgery: A Systematic Review and Meta-Analysis
Evidence supporting the routine use of TXA in paediatric cardiac surgery remains weak.
Protecting the Infant Brain During Cardiac Surgery: A Systematic Review
Prevention of brain injury during congenital heart surgery has focused on intraoperative and perioperative neuroprotection and neuromonitoring.
Pharmacokinetics of Tranexamic Acid in Patients Undergoing Cardiac Surgery with Use of Cardiopulmonary Bypass
We conducted a study to assess pharmacokinetics of high-dose tranexamic acid for 24 h after administration of the drug in patients undergoing cardiac surgery with cardiopulmonary bypass.
Hyperfibrinolysis is Common in Out-of-Hospital Cardiac Arrest: Results from a Prospective Observational Thromboelastometry Study
Routine use of fibrinolytic therapy in all patients with prolonged CPR cannot therefore be recommended.