In Vitro Comparison of Two Different Methods of Cell Washing
The objective of this study was to compare the product created by washing a unit of RBCs with the AutoLog autotransfusion device in the operating room to the washed products from a standard cell washer in the blood bank.
Impact of Experimental Haemodilution on Platelet Function, Thrombin Generation and Clot Firmness: Effects of Different Coagulation Factor Concentrates
The haemostatic alterations caused by haemodilution are multifactorial and affect both blood cells and coagulation.
Wet-Priming Extracorporeal Membrane Oxygenation Device Maintains Sterility for up to 35 Days of Follow-Up
Sterility was maintained in the ECMO circuits for up to 35 days.
Nutritional Imbalances during Extracorporeal Life Support
The aim of this chapter is to describe the changes induced by artificial membranes and the required therapies to optimize nutritional support.
Contemporary Results of Open Aortic Arch Surgery
Open aortic arch replacement can be performed with low operative mortality and stroke rates, especially in elective circumstances, by a team with particular focus on the procedure.
Preload Sensitivity in Cardiac Assist Devices
In this review, we stratify the preload sensitivity of 17 implantable cardiac assist devices relative to the native heart and discuss the effect of preload sensitivity on left ventricular volume unloading, levels of cardiac support, and the future development of continuous-flow total artificial heart technology.
Variations in the Application of Various Perfusion Technologies in Great Britain and Ireland–A National Survey
This study investigates variations in the application of these technologies throughout Great Britain and Ireland (GB & I).
Anticoagulation in Patients with Dilated Cardiomyopathy, Low Ejection Fraction and Sinus Rhythm: Back to the Drawing Board
Heart failure patients present an important thrombo-embolic risk, including symptomatic or silent peripheral arterial embolism, pulmonary embolism and stroke.
Transesophageal Echocardiography Probe Insertion Failure in Infants Undergoing Cardiac Surgery
A retrospective chart review of all neonates ≤4 kg who underwent cardiac surgery at our institution from 12/2001 to 12/2006 was performed. Patients who underwent operations that did not typically require TEE were excluded. Risk factors for TEE probe insertion failure were assessed.
O2 Delivery and CO2 Production during Cardiopulmonary Bypass as Determinants of Acute Kidney Injury
The experimental hypothesis was that nadir DO2 values and nadir DO2/VCO2 ratios during CPB would be independent predictors of AKI.
A Quantitative Comparison of Mechanical Blood Damage Parameters in Rotary Ventricular Assist Devices: Shear Stress, Exposure Time and Hemolysis Index
In this study, computational fluid dynamics (CFD) was used to calculate the hemodynamics in three clinical VADs and two investigational VADs and the shear stress, residence time, and hemolysis were investigated.
Potential of Gene Therapy as a Treatment for Heart Failure
Advances in understanding the molecular basis of myocardial dysfunction, together with the evolution of increasingly efficient gene transfer technology, make gene-based therapy a promising treatment option for heart conditions.