Intraoperative High-Dose Dexamethasone for Cardiac Surgery: A Randomized Controlled Trial
In our trial of adults undergoing cardiac surgery, the use of intraoperative dexamethasone did not reduce the 30-day incidence of major adverse events compared with placebo.
Central Venous Oxygen Saturation During Cardiopulmonary Bypass Predicts 3-Year Survival
The present report explores the connection between SvO2 during cardiopulmonary bypass (CPB) and survival after cardiac surgery.
Plutonium-238: An Ideal Power Source for Intracorporeal Ventricular Assist Devices?
Ventricular assist devices emerged as a widely used modality for treatment of end-stage heart failure; however, despite significant advances, external energy supply remains a problem contributing to significant patient morbidity and potential mortality.
Population Pharmacokinetics of Olprinone in Patients Undergoing Cardiac Surgery with Cardiopulmonary Bypass
Therefore, the purpose of this study was to determine olprinone pharmacokinetic parameters in a large population undergoing cardiac surgery with CPB.
Alloimmunosensitization in Left Ventricular Assist Device Recipients and Impact on Posttransplantation Outcome
Despite the clinical success of these devices, it has been reported that many patients bridged to transplantation with mechanical support develop circulating antibodies with potential donor reactivity.
A Recipe for Perioperative Cardioprotection: What Matters Most? The Ingredients or the Chef?
The question of what is the ideal anesthetic for patients with cardiovascular disease has been debated for nearly three decades, and similarly to the case for the use of perioperative beta blockers, the answer appears to be increasingly enigmatic.
Validation of a Perfusion Registry: Methodological Approach and Initial Findings
Although regional and national registries exist to measure and report performance of cardiac surgical programs, few registries exist dedicated to the practice of cardiopulmonary bypass (CPB). We developed and implemented a cardiovascular perfusion registry (Perfusion Measures and outcomes [PERForm] Registry) within the structure of the Michigan Society of Thoracic and Cardiovascular Surgeons (MSTCVS) to improve our understanding of the practice of CPB.
Development of a New Arterial Line Filter Design Using Computational Fluid Dynamics Analysis
This article reviews theoretical principles of micropore filter technology and outlines the development of a new arterial-line filter concept using computational fluid dynamics analysis.
Theoretical Treatise: Arterial Pressure during Aortic Surgery
This theoretical treatise predicts that blood pressure management should be temperature- and hematocrit-dependent. The target optimal blood pressure will vary during the course of surgery as a result of heating, cooling, and hemodilution.
The Effect of Acute Sleep Deprivation and Fatigue in Cardiovascular Perfusion Students: A Mixed Methods Study
Sleep deprivation as a result of long working hours has been associated with an increased risk of adverse events in healthcare professions but not in cardiovascular perfusion. The purpose of this study is to investigate the impact of sleep deprivation on cardiovascular perfusion students.
Heparin Therapy during Extracorporeal Circulation: Deriving anOptimal Activated Clotting Time during Cardiopulmonary Bypass for Isolated Coronary Artery Bypass Grafting
The effect of heparin dose, sensitivity, metabolism, patient size, elective/urgent, protamine reversal regime, returned pump blood volume and heparin content, and average ACT during CPB with regard to postoperative blood loss and resternotomy was examined in a consecutive series of patients undergoing isolated coronary artery bypass surgery.
A Novel Technique for Intra-aortic Balloon Positioning in the Intensive Care Unit
In this technique, we rely on the left radial arterial trace obliteration as the IABP catheter is pushed in along a guidewire as a marker for tip positioning.