Short-Acting P2Y12 Blockade to Reduce Platelet Dysfunction and Coagulopathy During Experimental Extracorporeal Circulation and Hypothermia
This experimental study tested P(2)Y(12) receptor blockade as an approach to protect platelets during ECC.
Low-Flow Antegrade Cerebral Perfusion Attenuates Early Renal and Intestinal Injury During Neonatal Aortic Arch Reconstruction
These results substantiate earlier suggestions that ACP provides more abdominal organ protection than DHCA in neonates undergoing aortic arch reconstruction.
Cold Reperfusion Before Rewarming Reduces Neurological Events after Deep Hypothermic Circulatory Arrest
Before rewarming, a 10-min period of cold perfusion significantly reduces incidence of NE.
A Modified Protocol for Retrograde Cerebral Perfusion: Magnetic Resonance Spectroscopy in Pigs
Application of the modified RCP protocol significantly improved cerebral energy conservation during HCA and accelerated energy recovery after rewarming.
Is it Worth Packing the Head with Ice in Patients Undergoing Deep Hypothermic Circulatory Arrest?
We conclude that topical head cooling with ice is of use during DHCA but not during rewarming following DHCA and that it may be possible to advance topical head cooling techniques using circulating water rather than packed ice.
Right Ventricular Dysfunction Following Continuous Flow Left Ventricular Assist Device Placement in 51 Patients: Predicators and Outcomes
The adjustment of septal deviation through gradual increase of the LVAD flow can prevent the acute RV dysfunction following LVAD placement.
Are Right Ventricular Risk Scores Useful?
The use of risk scores failed to predict the need of RV support after LVAD.
The Optimal Flow Rate for Antegrade Cerebral Perfusion During Deep Hypothermic Circulatory Arrest
Cerebral protection effects of ACP at 25 and 50 mL/kg/min were superior to that of ACP at 80 mL/kg/min as determined by cerebral markers, immunology, and histology.
Establishment of a Co-Culture Model for Studying Inflammation after Pediatric Cardiopulmonary Bypass: From Bench to Bedside
Our coculture model could be useful for studies on the mechanisms of CPB-induced inflammation.
Surgical Management by Means of Electroretinographic Examination During Extracorporeal Circulation
This exam can assess the defect of the waves indicative of insufficient ocular and brain perfusion of patients supported by ECC during cardiosurgical interventions.
Cerebral Protection during Controlled Hypoperfusion in a Piglet Model: Comparison of Moderate (25°C) versus Deep (18°C) Hypothermia at Various Flow Rates Using Intraoperative Measurements and Ex Vivo Investigation
The aim of this study was to evaluate the effectiveness and safety of controlled cerebral hypoperfusion at moderate (25°C) versus deep (18°C) hypothermia.
Intraoperative High-Dose Dexamethasone for Cardiac Surgery: A Randomized Controlled Trial
In our trial of adults undergoing cardiac surgery, the use of intraoperative dexamethasone did not reduce the 30-day incidence of major adverse events compared with placebo.