Preconditioning Protects the Heart in a Prolonged Uremic Condition
We conclude that although prolonged experimental uremia leads to severe metabolic changes and the development of a mild myocardial dysfunction, the cardioprotective effect of ischemic preconditioning is still preserved.
Rapamycin Protects against Myocardial Ischemia-Reperfusion Injury through JAK2-STAT3 Signaling Pathway
We propose that rapamycin is a novel and clinically relevant pharmacological strategy to target STAT3 activation for treatment of myocardial infarction.
High Fidelity Case-Based Simulation Debriefing: Everything You Need to Know
In this 30-minute talk, the authors take an in-depth look at how to debrief high-fidelity case-based simulation sessions, including discussion on debriefing theory, goals, approaches, and structure, as well as ways to create a supportive and safe learning environment, resulting in successful small group learning and self-reflection.
Insensible Water Loss from the Hilite 2400LT Oxygenator: An In Vitro Study
The aim of this study is to explore the degree to which free water loss occurs across a commonly used ECMO oxygenator, the polymethylpentene (PMP) membrane Hilite(®) 2400LT (Medos, Medizintechnik AG, Stolberg, Germany).
Endogenous Hydrogen Sulfide Mediates the Cardioprotection Induced by Ischemic Postconditioning in the Early Reperfusion Phase
The present study aimed to investigate the role of H(2)S in ischemic postconditioning (IPO) during the early period of reperfusion.
Speaking up is Related to Better Team Performance in Simulated Anesthesia Inductions: An Observational Study
This study provides empirical evidence and shows mechanisms for the positive relationship between speaking-up behavior and technical team performance.
Intralipid, A Clinically Safe Compound, Protects the Heart against Ischemia-Reperfusion Injury more Efficiently than Cyclosporine-A
Here we compared the cardioprotective effects of intralipid with cyclosporine-A, a potent inhibitor of the mitochondrial permeability transition pore opening.
Isoflurane Prevents Neurocognitive Dysfunction After Cardiopulmonary Bypass in Rats
Isoflurane has documented neuroprotective effects so the present authors hypothesized that isoflurane prevents the neurocognitive dysfunction in rats after CPB.
Red Blood Cell Transfusion Volume and Mortality among Patients Receiving Extracorporeal Membrane Oxygenation
Greater red blood cell transfusion volumes among patients supported with ECMO for non-cardiac indications are independently associated with an increase in odds of mortality.
Does Anemia Impact Hospital Readmissions after Coronary Artery Bypass Surgery
We conducted a single-center retrospective study of 2102 patients who had CABG in Ontario to determine whether anemia at hospital discharge was associated with increased 30-day hospital readmissions, readmission secondary to cardiac disease, and 30-day mortality using administrative data.
Exercise-Based Cardiac Rehabilitation Improves Hemodynamic Responses After Coronary Artery Bypass Graft Surgery
Cardiac rehabilitation significantly improves functional capacity and some hemodynamic responses post coronary artery bypass grafting. Therefore, patients need to be referred to rehabilitation units.
Beta-Adrenergic Receptor Polymorphisms and Cardiac Graft Function in Potential Organ Donors
We hypothesized that βAR polymorphisms predispose donor hearts to LV dysfunction after brain death.