Intralipid, A Clinically Safe Compound, Protects the Heart against Ischemia-Reperfusion Injury more Efficiently than Cyclosporine-A
Here we compared the cardioprotective effects of intralipid with cyclosporine-A, a potent inhibitor of the mitochondrial permeability transition pore opening.
Evolution of General Surgical Problems in Patients with Left Ventricular Assist Devices
Patients with LVADs frequently require consultation from noncardiac surgeons within the scope of general surgeons and often require operation.
Speaking up and Sharing Information Improves Trainee Neonatal Resuscitations
Teamwork behaviors of assertion and sharing information are 2 important mediators of efficiency and quality of resuscitations.
The Use of ECMO for Persistent Pulmonary Hypertension of the Newborn: A Decade of Experience
The objectives of this study were to use the Extracorporeal Life Support Organization Registry to review the outcomes of neonates with PPHN receiving ECMO, and to identify pre-ECMO variables that may be associated with increased mortality.
Cardioprotective Effect of Melatonin against Ischaemia/Reperfusion Damage
Melatonin, both in the picomolar and micromolar range, significantly reduces infarct size and improves functional recovery during reperfusion.
A Thrombus Susceptibility Comparison of Two Pulsatile Penn State 50 cc Left Ventricular Assist Device Designs
Results of this study indicate that the V-2 device had an overall lower propensity for thrombus formation in the current region of interest.
Teaching Behaviors in the Cardiac Surgery Simulation Environment
To understand how teaching behaviors contribute to simulation-based learning, we used a 7-category educational framework to assess the teaching behaviors used in basic skills training.
Isoflurane Prevents Neurocognitive Dysfunction After Cardiopulmonary Bypass in Rats
Isoflurane has documented neuroprotective effects so the present authors hypothesized that isoflurane prevents the neurocognitive dysfunction in rats after CPB.
Red Blood Cell Transfusion Volume and Mortality among Patients Receiving Extracorporeal Membrane Oxygenation
Greater red blood cell transfusion volumes among patients supported with ECMO for non-cardiac indications are independently associated with an increase in odds of mortality.
Update on Blunt Thoracic Aortic Injury: Fifteen-Year Single-Institution Experience
We report our experience with blunt thoracic aortic injury at a level 1 trauma center over the past 15 years.
In Vitro Clearance of Dexmedetomidine in Extracorporeal Membrane Oxygenation
An in vitro ECMO circuit was used to study the effects of both "new" and "old" membrane oxygenators on the clearance of dexmedetomidine over the course of 24 hours.
Perioperative Coagulation Management During Cardiac Surgery
Recent studies suggest that implementation of point-of-care testing in hemotherapy algorithms which inclose stepwise therapeutic escalation may reduce perioperative blood loss and the transfusion rate of allogenic blood products. This should improve patient's clinical outcome and reduce costs.