Update on Clinical Trials for the Prevention of Acute Kidney Injury in Patients Undergoing Cardiac Surgery
Effective therapeutic agents for the prevention and treatment of acute kidney injury (AKI) after cardiac surgery remain elusive despite the tremendous advances in surgical techniques, technology, and understanding of disease processes. Recent developments and their effect on the incidence of AKI after cardiac surgery are discussed.
Relevance of the Surgical Care Improvement Project on Glycemic Control in Patients Undergoing Cardiac Surgery Who Receive Continuous Insulin Infusions
This study was undertaken to (1) determine the incidence of SCIP outliers in patients receiving a continuous insulin infusion (CII) targeted to maintain perioperative serum glucose levels less than 180 mg/dL after cardiac surgery, (2) identify the profile of patients who are SCIP outliers, (3) determine whether SCIP outliers have increased morbidity and mortality, and (4) identify more relevant benchmarks for glycemic control in patients having cardiac surgery.
N-3 Polyunsaturated Fatty Acids to Prevent Atrial Fibrillation: Updated Systematic Review and Meta-Analysis of Randomized Controlled Trials
Electronic searches were conducted in Web of Science, Medline, Biological Abstracts, Journal Citation Reports, and the Cochrane Central Register of Controlled Trials databases. In addition, data from the recently completed FORωARD and OPERA trials were included. We included randomized controlled trials comparing treatment with n-3 PUFAs versus control to (1) prevent recurrent AF in patients who underwent reversion of AF or (2) prevent incident postoperative AF after cardiac surgery.
Effect of an Investigational Vaccine for Preventing Staphylococcus Aureus Infections after Cardiothoracic Surgery: A Randomized Trial
This study evaluates the efficacy and safety of preoperative vaccination in preventing serious postoperative S. aureus infection in patients undergoing cardiothoracic surgery.
The Challenge of Home Discharge with a Total Artificial Heart: The La Pitie Salpetriere Experience
Despite the morbidity and mortality occurring during the postimplantation period, home discharge with a TAH is possible. Portables drivers allow for a safe return home.
Interventions for Preventing Post-Operative Atrial Fibrillation in Patients Undergoing Heart Surgery
We conducted an update to a 2004 Cochrane systematic review and meta-analysis of the literature to gain a better understanding of the effectiveness of these interventions.
Minimally Invasive Approach Provides at Least Equivalent Results for Surgical Correction of Mitral Regurgitation: A Propensity-Matched Comparison
In appropriate patients with isolated mitral valve disease of any cause, a right minithoracotomy approach may be used without compromising clinical outcome.
Innate Immune Activation after Transfusion of Stored Red Blood Cells
In this narrative review, we explore the hypothesis that prolonged RBC storage results in elaboration of substances which may function as danger associated molecular pattern molecules that activate the innate immune system with consequences unfavorable to healthy homeostasis.
Antegrade and Retrograde Arterial Perfusion Strategy in Minimally Invasive Mitral-Valve Surgery: A Propensity Score Analysis on 1280 Patients
The aim of the present study was therefore to evaluate the impact on early outcome of retrograde arterial perfusion (RAP) strategy vs antegrade arterial perfusion strategy in a consecutive large cohort of patients who underwent minimally invasive mitral-valve surgery through a right minithoracotomy.
Use of Extracorporeal Life Support for Emergency Coronary Artery Bypass Grafting
The entire procedure was performed on a beating heart using a stabilizer during ECLS.
Extracorporeal Membrane Oxygenation with Double Venous Drainage
We report on a successful configuration strategy of extracorporeal membrane oxygenation(ECMO) in two consecutive cases of acute lung injury.
Blood Oxygenation and Decarboxylation Determinants during Venovenous ECMO for Respiratory Failure in Adults
For severe ARDS patients receiving femoro-jugular vv-ECMO, blood flow was the main determinant of arterial oxygenation