Effect of Fresh Red Blood Cell Transfusions on Clinical Outcomes in Premature, Very Low-Birth-Weight Infants: The ARIPI Randomized Trial
In this trial, the use of fresh RBCs compared with standard blood bank practice did not improve outcomes in premature, very low-birth-weight infants requiring a transfusion.
Effects of Magnesium Sulphate on Postoperative Coagulation, Measured by Rotational Thromboelastometry (ROTEM(®)).
Intra-operative infusion of magnesium sulphate seems to attenuate postoperative hypercoagulability by maintaining magnesium levels at the upper limit of the normal range.
Effects of Pre-Storage Leukoreduction on Stored Red Blood Cells Signaling: A Time-Course Evaluation from Shape to Proteome
The introduction of pre-storage leukoreduction in the preparation of standard RBCs intended for transfusion provided significant improvement in the quality of labile products and their post transfusion viability and effects, although the literature data are controversial.
Transfusion Immunomodulation – The Case for Leukoreduced and (Perhaps) Washed Transfusions
The present review will focus on two approaches, leukoreduction and saline washing, as means to reduce adverse transfusion outcomes.
Cell-Derived Microparticles in Stored Blood Products: Innocent-Bystanders or Effective Mediators of Post-Transfusion Reactions?
Plasma membrane-derived microvesicles or microparticles (MPs) are sub-cellular vesicles released upon shear stress, cell activation, injury or apoptosis.
The Influence of Heparin Resistance on Postoperative Complications in Patients Undergoing Coronary Surgery
Severe form of heparin resistance (expressed by the ACT less than 480 seconds after 400 U/kg heparin) was an independent predictor of death.
Increased Long-Term Mortality with Plasma Transfusion after Coronary Artery Bypass Surgery
This study explores the relation between the transfusion of different blood components and long-term mortality.
Fresh and Stored Red Blood Cell Transfusion Equivalently Induce Subclinical Pulmonary Gas Exchange Deficit in Normal Humans
We tested the hypothesis that transfusion can cause mild pulmonary dysfunction that has not been noticed clinically and is not sufficiently severe to fit the definition of transfusion-related acute lung injury.
Impact of Transfusion of Autologous 7- versus 42-Day-Old AS-3 Red Blood Cells on Tissue Oxygenation and the Microcirculation in Healthy Volunteers
Transfusion of 1 unit of 42-day-stored RBCs to healthy subjects has no overt detrimental effect on tissue oxygenation or the microcirculation assessed by clinically available monitors.
Peroperative Effects of Fresh Frozen Plasma and Antithrombin III on Heparin Sensitivity and Coagulation during Nitroglycerine Infusion in Coronary Artery Bypass Surgery
ATIII may be preferred to FFP in patients with heparin resistance due to NTG infusion undergoing CABGS.
Anticoagulation and Bleeding in Patients with Ventricular Assist Devices: Walking the Tightrope
A left ventricular assist device (LVAD) is a lifesaving therapy for end-stage heart failure, but it is associated with major complications such as bleeding and thrombosis.
Non-Invasive Estimation of Jugular Venous Oxygen Saturation: A Comparison Between Near Infrared Spectroscopy and Transcutaneous Venous Oximetry
Placement of cerebral oximetry patches directly over the internal jugular vein (as opposed to on the forehead) appeared to approximate internal jugular venous saturation better...