Fibrinogen Concentrate Therapy in Complex Cardiac Surgery
This study reports the initial clinical use of fibrinogen concentrate in complex cardiac surgery.
Haemostatic Therapy in Coronary Artery Bypass Graft Patients with Decreased Platelet Function: Comparison of Fibrinogen Concentrate with Allogeneic Blood Products
Fibrinogen concentrate administration increased the fibrin clot quality and helped achieve haemostasis.
The Age of Blood Evaluation (ABLE) Randomized Controlled Trial: Study Design
The "Age of Blood Evaluation" (ABLE) study (ISRCTN44878718) is a double-blind, multicenter, parallel randomized controlled clinical trial.
ABO Incompatible Platelets: Risks versus Benefit
This review summarizes recent developments in the area of ABO compatibility and platelet transfusion and examines the risks and benefits associated with transfusion practices allowing for platelet ABO incompatibility.
Processed Residual Pump Blood in Cardiac Surgery: The Processed Residual Blood in Cardiac Surgery Trial
Ultrafiltration of residual CPB volume in adults undergoing isolated CABG surgery does not reduce the need for transfusion or bleeding.
Transfusion Thresholds and other Strategies for Guiding Allogeneic Red Blood Cell Transfusion
The purpose of this review is to compare clinical outcomes in patients randomised to restrictive versus liberal transfusion thresholds (triggers).
Effect of Hospital Culture on Blood Transfusion in Cardiac Procedures
We sought to quantitate the contribution of hospital influence on individual surgeons' transfusion practices.
Fresh Red Blood Cell Transfusion and Short-Term Pulmonary, Immunologic, and Coagulation Status: A Randomized Clinical Trial
In this randomized clinical trial, no differences were noted in early measures of pulmonary function or in immunologic or coagulation status when comparing fresh versus standard issue single-unit RBC transfusion.
Preoperative Hemostasis and Its Association with Bleeding and Blood Component Transfusion Requirements in Cardiopulmonary Bypass Surgery
A standardized bleeding history may help to identify patients undergoing CPB surgery whose risk of bleeding is elevated.
Fibrinogen Function is Impaired in Whole Blood from Patients with Cyanotic Congenital Heart Disease
Patients with CCHD are hypocoagulable mainly due to impaired fibrinogen function.
Anticoagulation and Bleeding in Patients with Ventricular Assist Devices: Walking the Tightrope
A left ventricular assist device (LVAD) is a lifesaving therapy for end-stage heart failure, but it is associated with major complications such as bleeding and thrombosis.
Non-Invasive Estimation of Jugular Venous Oxygen Saturation: A Comparison Between Near Infrared Spectroscopy and Transcutaneous Venous Oximetry
Placement of cerebral oximetry patches directly over the internal jugular vein (as opposed to on the forehead) appeared to approximate internal jugular venous saturation better...