Use of Prothrombin Complex Concentrate for Excessive Bleeding after Cardiac Surgery
Administration of low-dose of PCC significantly decreased postoperative bleeding after CPB.
Longer Blood Storage is Associated with Suboptimal Outcomes in High-Risk Pediatric Cardiac Surgery
The freshest RBC units available should be used for pediatric cardiac operations expected to require more than 4 units or more than 150 mL/kg of allogeneic RBC transfusions, with no units more than 14 days old being transfused whenever possible.
Effect of Processing and Storage on Red Blood Cell Function In Vivo
Red blood cell (RBC) transfusion is indicated to improve oxygen delivery to tissue, and for no other purpose.
Fibrinogen Concentrate Therapy in Complex Cardiac Surgery
This study reports the initial clinical use of fibrinogen concentrate in complex cardiac surgery.
Haemostatic Therapy in Coronary Artery Bypass Graft Patients with Decreased Platelet Function: Comparison of Fibrinogen Concentrate with Allogeneic Blood Products
Fibrinogen concentrate administration increased the fibrin clot quality and helped achieve haemostasis.
The Age of Blood Evaluation (ABLE) Randomized Controlled Trial: Study Design
The "Age of Blood Evaluation" (ABLE) study (ISRCTN44878718) is a double-blind, multicenter, parallel randomized controlled clinical trial.
ABO Incompatible Platelets: Risks versus Benefit
This review summarizes recent developments in the area of ABO compatibility and platelet transfusion and examines the risks and benefits associated with transfusion practices allowing for platelet ABO incompatibility.
Processed Residual Pump Blood in Cardiac Surgery: The Processed Residual Blood in Cardiac Surgery Trial
Ultrafiltration of residual CPB volume in adults undergoing isolated CABG surgery does not reduce the need for transfusion or bleeding.
Transfusion Thresholds and other Strategies for Guiding Allogeneic Red Blood Cell Transfusion
The purpose of this review is to compare clinical outcomes in patients randomised to restrictive versus liberal transfusion thresholds (triggers).
Effect of Hospital Culture on Blood Transfusion in Cardiac Procedures
We sought to quantitate the contribution of hospital influence on individual surgeons' transfusion practices.
Fresh Red Blood Cell Transfusion and Short-Term Pulmonary, Immunologic, and Coagulation Status: A Randomized Clinical Trial
In this randomized clinical trial, no differences were noted in early measures of pulmonary function or in immunologic or coagulation status when comparing fresh versus standard issue single-unit RBC transfusion.
Preoperative Hemostasis and Its Association with Bleeding and Blood Component Transfusion Requirements in Cardiopulmonary Bypass Surgery
A standardized bleeding history may help to identify patients undergoing CPB surgery whose risk of bleeding is elevated.