PDGF Supplementation Alters Oxidative Events in Wound Healing Process: A Time Course Study
In the present study, we especially focused on investigating the effects of exogenous PDGF administration on oxidative events during cutaneous wound healing process.
Effects of Retrograde Autologous Priming on Blood Transfusion and Clinical Outcomes in Adults: A Meta-Analysis
Compared to conventional priming, RAP could reduce transfusion in adults significantly, but had no effect on clinical outcomes, comparing to conventional priming.
Evaluation of Coagulation Factors and Platelet Function from an Off-Line Modified Ultrafiltration Technique for Post-Cardiopulmonary Bypass Circuit Blood Recovery
This study evaluated the off-line MUF process of the Hemobag (HB, Global Blood Resources, Somers, CT, USA) to quantitate coagulation factor levels
Balancing the Benefits and Risks of Blood Transfusions in Patients undergoing Cardiac Surgery: A Propensity-Matched Analysis
The goal of this study was to compare operative mortality in propensity-matched cardiac surgery patients based on stratification of the preoperative HCT levels.
Relationship between Red Cell Storage Duration and Outcomes in Adults Receiving Red Cell Transfusions: A Systematic Review
In this systematic review, we could find no definitive argument to support the superiority of fresh over older RBCs for transfusion.
Increased Red Blood Cell Transfusions Are Associated with Worsening Outcomes in Pediatric Heart Transplant Patients
We investigated the relationship between clinical outcomes and the amount of blood transfused both during and after heart transplantation.
Adipose-Derived Stem Cells Weigh in as Novel Therapeutics for Acute Lung Injury
We discuss the advantages and potential limitations of using adipose-derived stem cells as therapeutics for human acute lung injury.
Stromal Cells from the Adipose Tissue-Derived Stromal Vascular Fraction and Culture Expanded AdiposeTissue-Derived Stromal/Stem Cells: A Joint Statement of the International Federation for Adipose Therapeutics (IFATS) and Science and the International So
The goal of this paper is to provide initial guidance for the scientific community working with adipose-derived cells and to facilitate development of international standards based on reproducible parameters.
Mesenchymal Stem Cell Therapy in Osteoarthritis: Advanced Tissue Repair or Intervention with Smouldering Synovial Activation
Desando and co-workers report in Arthritis Research & Therapy that intra-articular delivery of adipose-derived stem cells attenuates progression of synovial activation and joint destruction in osteoarthritis in an experimental rabbit model. Clinical studies are warranted to see whether this approach might be a novel way to combat development of joint destruction in inflammatory subtypes of osteoarthritis.
Long-Term Detection of Human Adipose Derived Mesenchymal Stem Cells After Intra-Articular Injection
These data argue for the feasibility and safety of using intra-articular (IA) delivery of human adipose-derived stem cell (hASC) for the treatment of rheumatic diseases affecting the joints.
Extracts of Adipose Derived Stem Cells Slows Progression in the R6/2 Model of Huntington’s Disease
Stem cell transplantation has been investigated as a therapeutic strategy to treat the Huntington's disease (HD). Considering clinical feasibility and safety, injection of cell-free extracts of ASCs (ASCs-E) could be effective and safe strategy for HD patients, comparable to the stem cell therapy. Findings from our study provide possible strategy to inhibit HD progression and reasonable resources for treatment.
Adipose-Derived Stem Cells: Fatty Potentials for Therapy
The multi-lineage differentiation capacity, unique immunobiological properties and secretome of Adipose-derived stem cells (ASCs) offer tremendous therapeutic potentials in regenerative medicine.