Adipose-Derived Stem Cells: Fatty Potentials for Therapy
The multi-lineage differentiation capacity, unique immunobiological properties and secretome of Adipose-derived stem cells (ASCs) offer tremendous therapeutic potentials in regenerative medicine.
Decreased Erythrocyte Deformability After Transfusion and the Effects of Erythrocyte Storage Duration
The findings demonstrate that increased duration of erythrocyte storage is associated with decreased cell membrane deformability and that these changes are not readily reversible after transfusion.
Regenerate Augmentation with Bone Marrow Concentrate after Traumatic Bone Loss
The aim of this feasibility study was to investigate the potential of bone marrow aspiration concentrate (BMAC) for percutaneous regenerate augmentation to accelerate bony consolidation of the regenerate.
In Vivo Comparison of the Bone Regeneration Capability of Human Bone Marrow Concentrates vs. Platelet-Rich Plasma
The objective of this study was to evaluate the effects of human BMAC and PRP in combination with β-tricalcium phosphate (β-TCP) on promoting initial bone augmentation in an immunodeficient mouse model.
Establishing proof of concept: Platelet-Rich Plasma and Bone Marrow Aspirate Concentrate may Improve Cartilage Repair Following Surgical Treatment for Osteochondral Lesions of the Talus
The basic science literature therefore establishes the proof of concept that biological adjuncts may improve cartilage repair when used in conjunction with reparative and replacement treatment strategies for osteochondral lesions of the talus.
The Positive Effects of Different platelet-Rich Plasma Methods on Human Muscle, Bone, and Tendon Cells
The primary findings of this study suggest the application of different PRP separations may result in a potential beneficial effect on the clinically relevant target cells in vitro.
Platelet-Rich Plasma Versus Focused Shock Waves in the Treatment of Jumper’s Knee in Athletes
Therapeutic injections of PRP lead to better midterm clinical results compared with focused ESWT in the treatment of jumper's knee in athletes.
Platelet-Rich Plasma (PRP): An Adjuvant to Hasten Hamstring Muscle Recovery. A Randomized Controlled Trial Protocol
This study protocol proposes a rigorous and potential significant evaluation of PRP use for grade-2 hamstring injury.
Unique Antimicrobial Effects of Platelet-Rich Plasma and Its Efficacy as a Prophylaxis to Prevent Implant-Associated Spinal Infection
Compared to the infection controls, PRP treatment results in significant reduction in bacterial colonies in bone samples at all time points studied (i.e. 1, 2, and 3 weeks) and significant increase in mineralized tissues (thereby better bone healing) at postoperative weeks 2 and 3.PRP therefore may be a useful adjunct strategy against postoperative implant-associated infections.
Platelet-Rich Plasma Application in the Management of Chronic Tendinopathies
Platelets release various cytokines and growth factors which promote angiogenesis, tissue remodeling, and wound healing. We made an extended literature review of the use of PRP in chronic tendinopathies: epicondylitis, rotator cuff, patellar and calcaneal tendinopathies, and plantar fasciitis.
Outcomes after Ultrasound-Guided Platelet-Rich Plasma Injections for Chronic Tendinopathy: A Multicenter, Retrospective Review
In this retrospective study, in which we evaluated administration of PRP for chronic tendinopathy, we found that the majority of patients reported a moderate (>50%) improvement in pain symptoms.
Platelet Rich Plasma. A New Treatment Tool for the Rheumatologist
In the following review we will analyze in detail its principles, preparation, and management regimes. We will reflect on potential adverse effects and, finally, there will be a critical analysis of the scientific evidence that supports its potential use in the rheumatology clinic.