Platelet Rich Plasma Therapy: Inflammatory Molecules Involved in Tissue Healing
The biological properties of platelets has lead platelet rich plasma therapy (PRP) to be considered an innovative and promising approach that has been extended to many field of medicine, ranging from non-union defects, bone fractures, spinal fusion, bone implant and osteointegration, joint arthroplasty, to the treatment of several traumatic or degenerative pathologies of tendons, cartilage and ligaments.
Autologous Bone Marrow Concentrate: Review and Application of a Novel Intra-Articular Orthobiologic for Cartilage Disease
The potential of cell-based orthobiologic injection therapies (pertaining to therapeutic injectables that aim to restore the biologic environment and/or structural components of diseased or damaged musculoskeletal tissue) is of tremendous interest for younger, more active patients, and is even more appealing in that such therapy can be delivered at point-of-care in the clinic during an office visit.
Treatment of Knee Chondropathy with Platelet Rich Plasma. Preliminary Results at 6 Months of Follow-Up with Only One Injection
Recently, PRP have been used to treat early moderate chondropathies. Here we show the preliminary results of 30 patients affected by chondropathy of the knee after 6 months treated with a single intrarticular injection of PRP.
A Systematic Review of Antifibrinolytics and Massive Injury
The coagulopathy induced by trauma is independently associated with mortality, increased transfusion requirements, multiple organ dysfunction, infections, increased intensive care unit (ICU) length of stay, and costs.
Management of Blood Transfusion in Aortic Valve Surgery: Impact of a Blood Conservation Strategy
There are limited data in the literature concerning the effect of a blood conservation strategy (BCS) on aortic valve replacement (AVR) patients.
Simultaneous Inflammatory Pseudotumors of the Coronary Arteries and Abdominal Aorta
We herein report a rare case of cardiac and abdominal aortic inflammatory pseudotumors (IPTs). The pathological diagnosis was IPT, which was judged to be inoperable because of its anatomical location and the fact that the patient was a Jehovah's Witness, which precluded the administration of heterologous blood transfusions.
Desmopressin for Reducing Postoperative Blood Loss and Transfusion Requirements Following Cardiac Surgery in Adults
A best evidence topic in cardiac surgery was written according to a structured protocol. The question addressed was, in adult patients undergoingcardiac surgery requiring extracorporeal cardiopulmonary bypass (CPB), does administration of desmopressin acetate (DDAVP) reduce postoperativeblood loss and transfusion requirements?
Minimally Invasive Mitral Surgery Through Right Mini-Thoracotomy Under Direct Vision
Based on our extensive experience we believe that mitral valve repair through a right mini-thoracotomy provides a durable and safe alternative to a traditional sternotomy with the benefits of improved cosmesis, reduced post-operative pain, less blood loss with fewer blood transfusions, fewer infections, shorter length of stay, and faster return to activity.
Association of Plasma Dilution with Cardiopulmonary Bypass-Associated Bleeding and Morbidity
To investigate the relationship of cardiopulmonary bypass-associated plasma dilution with blood product transfusion and postoperative morbidity.
The Least of 3 Evils: Exposure to Red Blood Cell Transfusion, Anemia, or Both?
We aimed to clarify the effects of anemia, transfusion, and their combination to identify which imposes the greatest risk of end-organ dysfunction and mortality.
Comparison of Results of Autologous Versus Homologous Blood Transfusion in Open-Heart Surgery
The aim of this study was to determine a method to decrease the use of homologous blood during open heart surgery using a simple blood conservation protocol.
Fibrinogen Recovery and Changes in Fibrin-Based Clot Firmness after Cryoprecipitate Administration in Patients Undergoing Aortic Surgery Involving Deep Hypothermic Circulatory Arrest
Cryoprecipitate may be used to treat bleeding in cardiac surgery. Its effects on plasma fibrinogen and fibrin clotting in this setting are poorly defined.