Enhancing Intervertebral Disc Repair and Regeneration Through Biology: Platelet-Rich Plasma as an Alternative Strategy
This review describes the current understanding of intervertebral disc degeneration (IDD) and related biological therapeutic strategies, especially the promising prospects of PRP treatment.
Comparison of Two Doses of Tranexamic Acid in Adults Undergoing Cardiac Surgery with Cardiopulmonary Bypass
The optimal dose of tranexamic acid (TA) is still an issue. The authors compared two doses of TA during cardiac surgery in a multicenter, double-blinded, randomized study.
Combined Treatment of Ulinastatin and Tranexamic Acid Provides Beneficial Effects by Inhibiting Inflammatory and Fibrinolytic Response in Patients Undergoing Heart Valve Replacement Surgery
We investigated the effect of ulinastatin and tranexamic acid administered alone or in combination on inflammatory cytokines and fibrinolytic system in patients undergoing heart valve replacement surgery during cardiopulmonary bypass (CPB).
The Biomechanics and Histological Effects of Platelet-Rich Plasma on Fracture Healing
Platelet-rich plasma (PRP) includes growth factors and proteins that accelerate and stimulate bone regeneration and tissue recovery. The aim of this study was to evaluate the effects of PRP on fracture healing in terms of biomechanics and histology.
Sensory Improvement of Leprosy Peripheral Neuropathy in Patients Treated with Perineural Injection of Platelet-Rich Plasma
This study shows that perineural PRP injection could promote improvement of peripheral neuropathy sensibility in patients with leprosy.
Autologous Blood Derived Signaling Proteins for Tendon and Muscle Therapy in Sports Medicine Higher Concentration of Growth Factors and Cytokines in Orthokine VS in ACP
We compared 2 none-PRP techniques: ORTHOKINE (Oe) for Autologous Conditioned Serum (ACS) and ACP (Ax) for autologous plasma (AP)
Does Tranexamic Acid Stop Haemoptysis
Current best evidence indicates that tranexamic acid may reduce both the duration and volume of bleeding, with low risk of short-term thromboembolic complications, in patients with haemoptysis.
Cardiac Surgery in a Patient with Severe Thrombocytopenia: How Low is Too Low
We report a case of severe thrombocytopenia (19 × 10 9 /L) where coronary artery bypass grafting was performed with minimal blood loss post-operatively, discuss the patient's management and provide insights while dealing with such patients.
Comparison of Epsilon Aminocaproic Acid and Tranexamic Acid in Thoracic Aortic Surgery: Clinical Efficacy and Safety
This study evaluates the efficacy and safety of tranexamic acid (TXA) versus epsilon aminocaproic acid (EACA) in patients undergoing thoracic aortic surgery.
How Effective are Injection Treatments for Lateral Epicondylitis
We compared the effectiveness, after 3 months, of a single injection of platelet-rich plasma (PRP), glucocorticoid (GC), or saline in reducing pain in lateral epicondylitis.
Achilles Tendinopathy Management: A Pilot Randomized Controlled Trial Comparing Platelet-Rich Plasma Injection with an Eccentric Loading Programme
We conducted a pilot randomized controlled trial to evaluate the feasibility of conducting a larger trial to evaluate the difference in Victorian Institute of Sports Assessment-Achilles (VISA-A) scores at six months between patients with Achilles tendinopathy treated with a platelet-rich plasma (PRP) injection compared with an eccentric loading programme.
Antithrombotic Strategies in Children Receiving Long-Term Berlin Heart EXCOR Ventricular Assist Device Therapy
The use of bivalirudin and epoprostenol infusions as an alternate anti-thrombotic (AT) regimen in pediatric VAD patients was reviewed.