Augmentation of Thrombin Generation in Neonates Undergoing Cardiopulmonary Bypass
We compared recombinant activated factor VII (rFVIIa) with three-factor prothrombin complex concentrate (3F-PCC) for the ability to augment thrombin generation (TG) in neonatal plasma after cardiopulmonary bypass (CPB).
Morbidity But Not Mortality Is Decreased After Off-Pump Coronary Artery Bypass Surgery
This retrospective study compared outcomes between on-pump and off-pump CABG from a large multicenter cohort of propensity-matched patients.
Identification of Modifiable Risk Factors for Acute Kidney Injury after Coronary Artery Bypass Graft Surgery in an Asian Population
We aimed to ascertain whether the lowest hematocrit during CPB, preoperative anemia, and intraoperative transfusion remained as independent modifiable risk factors associated with AKI in our prospective cohort of Asians.
Fibrinogen Recovery and Changes in Fibrin-Based Clot Firmness after Cryoprecipitate Administration in Patients Undergoing Aortic Surgery Involving Deep Hypothermic Circulatory Arrest
Cryoprecipitate may be used to treat bleeding in cardiac surgery. Its effects on plasma fibrinogen and fibrin clotting in this setting are poorly defined.
Augmentation of Thrombin Generation in Neonates Undergoing Cardiopulmonary Bypass
We compared recombinant activated factor VII (rFVIIa) with three-factor prothrombin complex concentrate (3F-PCC) for the ability to augment thrombin generation (TG) in neonatal plasma after cardiopulmonary bypass (CPB).
Safety and Effects of Two Red Blood Cell Transfusion Strategies in Pediatric Cardiac Surgery Patients: A Randomized Controlled Trial
For patients with a non-cyanotic congenital heart defect undergoing elective cardiac surgery, a restrictive RBC transfusion policy (threshold of Hb 8.0 g/dl) during the entire perioperative period is safe, leads to a shorter hospital stay and is less expensive.
Is Dilutional Coagulopathy Induced by Different Colloids Reversible by Replacement of Fibrinogen and Factor XIII Concentrates?
Coagulation and platelet function are impaired by all 3 colloids.
Red Blood Cell Transfusion: What is the Evidence When to Transfuse?
A restrictive transfusion strategy of administering red blood cell transfusion in patients with hemoglobin concentration of 7-8 g/dl in most patients is supported by randomized clinical trials.
Comparison of Epsilon Aminocaproic Acid and Tranexamic Acid in Thoracic Aortic Surgery: Clinical Efficacy and Safety
This study evaluates the efficacy and safety of tranexamic acid (TXA) versus epsilon aminocaproic acid (EACA) in patients undergoing thoracic aortic surgery.
How Effective are Injection Treatments for Lateral Epicondylitis
We compared the effectiveness, after 3 months, of a single injection of platelet-rich plasma (PRP), glucocorticoid (GC), or saline in reducing pain in lateral epicondylitis.
Achilles Tendinopathy Management: A Pilot Randomized Controlled Trial Comparing Platelet-Rich Plasma Injection with an Eccentric Loading Programme
We conducted a pilot randomized controlled trial to evaluate the feasibility of conducting a larger trial to evaluate the difference in Victorian Institute of Sports Assessment-Achilles (VISA-A) scores at six months between patients with Achilles tendinopathy treated with a platelet-rich plasma (PRP) injection compared with an eccentric loading programme.
Comparison of the Effects of Albumin 5%, Hydroxyethyl Starch 130/0.4 6%, and Ringer’s Lactate on Blood Loss and Coagulation after Cardiac Surgery
We randomly assigned 240 patients undergoing elective cardiac surgery to receive up to 50 ml kg-1 day-1 of either HA, HES, or Ringer's lactate (RL) as the main infusion fluid perioperatively.