Evaluation of a Novel Transfusion Algorithm Employing Point-of-care Coagulation Assays in Cardiac Surgery: A Retrospective Cohort Study with Interrupted Time-Series Analysis
This study evaluated a novel transfusion algorithm that uses point-of-care coagulation testing.
Platelet Function During Cardiopulmonary Bypass Using Multiple Electrode Aggregometry: Comparison of Centrifugal and Roller Pumps
Blood trauma may be lower with centrifugal pumps (CPs) than with roller pumps (RPs) during cardiopulmonary bypass (CPB), because, unlike RPs, CPs do not compress the tubing, and shear stress is considered lower in CPs than in RPs. However, relative platelet function remains unclear. Using multiple electrode aggregometry (MEA), we compared platelet function with CP and RP.
Pathophysiology of Cardiopulmonary Bypass: Current Strategies for the Prevention and Treatment of Anemia, Coagulopathy, and Organ Dysfunction
In this review, pathophysiological aspects of CPB are considered from a practical point of view, and preventive strategies for hemodilutional anemia, coagulopathy, inflammation, metabolic derangement, and neurocognitive and renal dysfunction are discussed.
Protamine Requirements in Cardiac Surgery: Effect of Changes in the Heparin Reference Standard
UFH (unfractionated heparin) and protamine are integral to cardiac surgery, and inappropriate dosing can predispose to coagulopathy and hemorrhage.
Evidence-Based Use of FFP: the Influence of a Priming Strategy Without FFP During CPB on Postoperative Coagulation and Recovery in Pediatric Patients
Our present study observed the effects of a priming strategy without fresh frozen plasma (FFP) during cardiopulmonary bypass (CPB) on postoperative coagulation and clinical recovery in pediatric patients, aiming to supply new evidence for evidence-based use of FFP.
The Impact of Hydroxyethyl Starches in Cardiac Surgery: A Meta-Analysis
Recent studies in septic patients showed that adverse effects of hydroxyethyl starches (HES) possibly outweigh their benefits
Magnitude of Anemia at Discharge Increases 30-Day Hospital Readmissions
Anemia during hospitalization is associated with poor health outcomes
A Polymicrobial Outbreak of Surgical Site Infections following Cardiac Surgery at a Community Hospital in Florida, 2011-2012
We describe an outbreak of 22 sternal surgical site infections following cardiac surgery
Recent Advances in the Diagnosis and Treatment of Heparin-Induced Thrombocytopenia
Heparin-induced thrombocytopenia (HIT) is a drug-mediated, prothrombotic disorder
Safety, Efficacy and Response to a Hydrocortisone Rescue Therapy Protocol in Children with Refractory Hypotension After Cardiopulmonal Bypass
Little is known about which paediatric patients respond to hydrocortisone rescue therapy
The Use of an Extracorporeal Membrane Oxygenation Anticoagulation Laboratory Protocol Is Associated With Decreased Blood Product Use, Decreased Hemorrhagic Complications, and Increased Circuit Life
We performed a retrospective chart review to determine outcomes for patients placed on extracorporeal membrane oxygenation prior to and after the initiation of our anticoagulation laboratory protocol.
Overview of Extracorporeal Membrane Oxygenation in Cardiogenic Shock
The purpose of this article was to review cardiogenic shock etiologies, the role of ECMO, and to discuss the transition process of implementing a nurse-run ECMO program.