Avoidance of Bleeding During Surgery in Patients Receiving Anticoagulant and/or Antiplatelet Therapy : Pharmacokinetic and Pharmacodynamic Considerations
Perioperative management of chronically anticoagulated patients and/or patients treated with antiplatelet therapy is a complex medical problem.
Sinus Floor Augmentation With Simultaneous Placement of Dental Implants in the Presence of Platelet-Rich Plasma or Recombinant Human Bone Morphogenetic Protein-7
The aim of the present study was to evaluate the possible benefit of platelet-rich plasma (PRP) in sinus grafting as compared with recombinant human bone morphogenetic protein-7 (rhBMP-7).
Cytomedix, Inc. Expands Patent Litigation Representation by Engaging Leading Litigation Firm
Cytomedix, Inc. (OTC BB:CYME.OB - News) today announced an expansion of the company's patent litigation legal representation with the engagement of Fish & Richardson on a contingent fee basis.
Identification of Pressure Passive Cerebral Perfusion and Its Mediators after Infant Cardiac Surgery
Absctract: Cerebrovascular pressure autoregulation (CPA) regulates cerebral blood flow (CBF) in relation to changes in mean arterial blood pressure (MAP). Identification of […]
Red Blood Cell Aggregation During Cardiopulmonary Bypass: A Pathogenic Cofactor in Endothelial Cell Activation?
RBC aggregation significantly drooped as consequence of blood dilution and blood–material interaction.
Near-Infrared Spectroscopy for Monitoring Cerebral Ischemia During Selective Cerebral Perfusion
A sustained drop in rSO2 during aortic surgery is closely related to the occurrence of neurological events following surgery.
Red Blood Cell Aggregation During Cardiopulmonary Bypass: A Pathogenic Cofactor in Endothelial Cell Activation?
RBC aggregation significantly drooped as consequence of blood dilution and blood–material interaction.
Reduced Complement Activation During Cardiopulmonary Bypass Does Not Affect the Postoperative Acute Phase Response
Material-induced reduction of the inflammatory response during CPB does not affect the postoperative acute phase response.
Cerebral Activation of Mitogen-Activated Protein Kinases After Circulatory Arrest and Low Flow Cardiopulmonary Bypass
Our results indicate that phosphorylated extracellular regulated kinase 1/2 may play a prominent role in early cerebral ischemia-reperfusion injury and endothelial dysfunction.
How Much Heparin Do We Really Need to Go on Pump? A Rethink of Current Practices
Patients receiving lower dose of heparin had lower postoperative blood loss.
The Effect of Methylprednisolone Treatment on the Cardiopulmonary Bypass-Induced Systemic Inflammatory Response
The results indicate that a single low-dose of methylprednisolone (10mg/kg) reduces the inflammatory reaction during and after CPB, by inhibition of proinflammatory cytokine release and OFR generation after release of the aortic cross-clamp.
The Short Term Effects of Cardiopulmonary Bypass on Neurologic Function in Children and Young Adults
There are no marked adverse neurologic effects of CPB in school-age children and young adults undergoing non-complex open-heart surgery.