Thrombus Growth and Embolism on Tissue Factor-Bearing Collagen Surfaces under Flow: Role of Thrombin with and without Fibrin
At sites of vascular injury, thrombin is an important mediator in thrombus growth and stability.
Bivalirudin and Post-Cardiotomy ECMO: A Word of Caution
Bivalirudin has been proposed as the sole anticoagulant in patients under extracorporeal membrane oxygenation (ECMO) or cardiopulmonary bypass.
The Effects of Conventional Extracorporeal Circulation Versus Miniaturized Extracorporeal Circulation on Microcirculation During Cardiopulmonary Bypass-Assisted Coronary Artery Bypass Graft Surgery
To reduce the complications associated with cardiopulmonary bypass (CPB) during cardiac surgery, many modifications have been made to conventional extracorporeal circulation systems.
Pharmacokinetic Changes in Patients Receiving Extracorporeal Membrane Oxygenation
Extracorporeal membrane oxygenation further complicates the management of critically ill patients who already have profound physiologic derangements with consequent altered pharmacokinetics.
Eye-Tracking Analysis of Skilled Performance in Clinical Extracorporeal Circulation
Eye-tracking data on four perfusionists were recorded while they were manipulating the ECC during a series of cardiovascular surgeries.
Long-term Mechanical Circulatory Support (Destination Therapy): On Track to Compete with Heart Transplantation?
Average 2-year survival after cardiac transplantation is approximately 80%.
Change in Heparin Potency and Effects on the Activated Clotting Time in Children Undergoing Cardiopulmonary Bypass
In this investigation we provide objective evidence that the level of anticoagulation after the initial pre-CPB heparin bolus as assessed by the ACT is significantly less with use of the new heparin.
Mechanical Circulatory Support for Cardiogenic Shock
In this review, we discuss the role of each of these circulatory support devices in the management of acute cardiac failure.
The Effect of Cardiopulmonary Bypass Prime Volume on the Need for Blood Transfusion after Pediatric Cardiac Surgery
There is increasing awareness that erythrocyte transfusions after pediatric cardiac surgery have deleterious effects.
Optimal Intraoperative Anticoagulation Strategy in Patients Undergoing Off-Pump Coronary Artery Bypass
The question addressed was what the optimal intraoperative anticoagulation strategy should be in patients undergoing off-pump coronary artery bypass graft (CABG) surgery
Washing of Banked Blood by Three Different Blood Salvage Devices
Washing improves the quality of stored RBCs, and autotransfusion devices have been proposed for intraoperative processing, but these devices were designed for diluted wound blood, and limited data on their performance with RBCs are available.
Cerebral and Lower Limb Near-Infrared Spectroscopy in Adults on Extracorporeal Membrane Oxygenation
Percutaneous femoral venoarterial (VA) or jugular venovenous (VV) extracorporeal membrane oxygenation (ECMO) can result in delivery of hypoxic blood to the brain, coronaries, and upper extremities