Platelet Mapping as Part of Modified Thromboelastography (TEG®) in Patients Undergoing Cardiac Surgery and Cardiopulmonary Bypass
The platelet-mapping assay of the thromboelastograph was used to measure platelet aggregation and to examine the effect of cardiopulmonary bypass on multiple platelet receptors and the role of altered receptor activity in postoperative bleeding.
Hyperfibrinolysis is Common in Out-of-Hospital Cardiac Arrest: Results from a Prospective Observational Thromboelastometry Study
Routine use of fibrinolytic therapy in all patients with prolonged CPR cannot therefore be recommended.
The Impact of Hematocrit on Fibrin Clot Formation Assessed by Rotational Thromboelastometry
Therefore, in the current study we investigated the influence of perioperative hematocrit changes on FIBTEM and fibrinogen measurements.
Reoperation for Bleeding in Cardiac Surgery
To reduce the rate of reoperations and mortality due to postoperative bleeding, we aim to identify risk factors that predict reoperation.
Is There a Suitable Method of Anticoagulation in Pregnant Patients with Mechanical Prosthetic Heart Valves?
A best evidence topic was written according to a structured protocol in order to identify the mode of anticoagulation that has the best safety profile for both the mother and the foetus in pregnant patients with mechanical prosthetic heart valves.
Prohemostatic Treatment in Cardiac Surgery
This article will discuss pharmacological agents including antifibrinolytics, protamine, desmopressin, fibrinogen, purified protein concentrates, recombinant factor VIIa, factor XIII, and topical agents used in cardiac surgery.
Perioperative Red Blood Cell Transfusion: Harmful or Beneficial to the Patient?
This review focuses on the physiology of oxygen transport, the hazards of acute anemia, the hazards of RBC transfusion, and the literature putting these problems into perspective.
Early Platelet Dysfunction: An Unrecognized Role in the Acute Coagulopathy of Trauma
In this study, we show that platelet dysfunction is manifest after major trauma and before substantial fluid or blood administration.
Aprotinin Revisited
The present review revisits the aprotinin controversy.
Effect of a Single Bolus of Methylene Blue Prophylaxis on Vasopressor and Transfusion Requirement in Infective Endocarditis Patients Undergoing Cardiac Surgery
We aimed to evaluate the effect of prophylactic MB administration before CPB on vasopressor and transfusion requirements in patients with IE undergoing valvular heart surgery (VHS).
Pharmacokinetics of Tranexamic Acid in Patients Undergoing Cardiac Surgery with Use of Cardiopulmonary Bypass
We conducted a study to assess pharmacokinetics of high-dose tranexamic acid for 24 h after administration of the drug in patients undergoing cardiac surgery with cardiopulmonary bypass.
How Do We Integrate Thromboelastography with Perioperative Transfusion Management?
In summary, we have found TEG to be useful in a variety of perioperative situations at our institution and potentially useful in other acute care settings such as the emergency department, the maternity unit, and many of the intensive care units.