Effect of Fresh Red Blood Cell Transfusions on Clinical Outcomes in Premature, Very Low-Birth-Weight Infants: The ARIPI Randomized Trial
In this trial, the use of fresh RBCs compared with standard blood bank practice did not improve outcomes in premature, very low-birth-weight infants requiring a transfusion.
Transfusion Thresholds and other Strategies for Guiding Allogeneic Red Blood Cell Transfusion
The purpose of this review is to compare clinical outcomes in patients randomised to restrictive versus liberal transfusion thresholds (triggers).
Prolonged Central Venous Desaturation Measured by Continuous Oximetry is Associated with Adverse Outcomes in Pediatric Cardiac Surgery
We demonstrate that ScvO₂ desaturations by continuous oximetry are associated with major adverse events in pediatric patients undergoing cardiac surgery.
Near-Infrared Spectroscopy Cerebral and Somatic (Renal) Oxygen Saturation Correlation to Continuous Venous Oxygen Saturation via Intravenous Oximetry Catheter
In this small cohort of pediatric patients undergoing heart surgery, there was a moderate but statistically significant correlation between the ScvO(2)-catheter and the NIRS-C values.
What Blood Temperature for an Ex Vivo Extracorporeal Circuit?
Investigators in this field must be aware of the fact that blood temperature is a crucial confounding parameter and the type of "background noise" they will face depending on the strategy adopted.
Fibrinogen Function is Impaired in Whole Blood from Patients with Cyanotic Congenital Heart Disease
Patients with CCHD are hypocoagulable mainly due to impaired fibrinogen function.
Preservation Solution Supplemented with Biliverdin Prevents Lung Cold Ischaemia/Reperfusion Injury
This study demonstrates that the exposure of the lung grafts to BV during cold storage can impart potent cytoprotective effects to lung cold ischaemia/reperfusion injury and significantly improve the lung graft function following extended cold preservation and transplantation by the mechanism of a reduction in oxidative injury and following inflammatory events.
Acute Neurological Complications after Pediatric Cardiac Surgery: Still a Long Way to Go
Our incidence of neurological complications after cardiac surgery is similar to that previously described.
Increased Risk of Acute Kidney Injury in Patients Undergoing Tricuspid Valve Surgery
We aimed to determine which patients undergoing tricuspid valve (TV) surgery are at increased risk for acute kidney injury (AKI).
Insufflation of Hydrogen Gas Restrains the Inflammatory Response of Cardiopulmonary Bypass in a Rat Model
We suggest that H(2) insufflation is a possible new potential therapy for counteracting CPB-induced systemic inflammation.
Selective Pulmonary Pulsatile Perfusion with Oxygenated Blood During Cardiopulmonary Bypass Attenuates Lung Tissue Inflammation but Does Not Affect Circulating Cytokine Levels
Improved respiratory outcome has been shown after selective pulsatile pulmonary perfusion (sPPP) during cardiopulmonary bypass (CPB).
Increased Long-Term Mortality with Plasma Transfusion after Coronary Artery Bypass Surgery
This study explores the relation between the transfusion of different blood components and long-term mortality.