PIRS as a QA and QI Tool (EP Video)
Jane Ottens discusses the use of PIRS as a QA and QI Tool (29:45 minutes).
Cell-Derived Microparticles in Stored Blood Products: Innocent-Bystanders or Effective Mediators of Post-Transfusion Reactions?
Plasma membrane-derived microvesicles or microparticles (MPs) are sub-cellular vesicles released upon shear stress, cell activation, injury or apoptosis.
Longer Blood Storage is Associated with Suboptimal Outcomes in High-Risk Pediatric Cardiac Surgery
The freshest RBC units available should be used for pediatric cardiac operations expected to require more than 4 units or more than 150 mL/kg of allogeneic RBC transfusions, with no units more than 14 days old being transfused whenever possible.
Fluid Balance as an Early Indicator of Acute Kidney Injury in CV Surgery
We hypothesized that positive fluid balance (FB) is the result of intraoperative kidney injury and associated renal vasoconstriction, and therefore may be an early clinical indicator of acute kidney injury (AKI).
Effect of Processing and Storage on Red Blood Cell Function In Vivo
Red blood cell (RBC) transfusion is indicated to improve oxygen delivery to tissue, and for no other purpose.
Use of Prothrombin Complex Concentrate for Excessive Bleeding after Cardiac Surgery
Administration of low-dose of PCC significantly decreased postoperative bleeding after CPB.
Fresh and Stored Red Blood Cell Transfusion Equivalently Induce Subclinical Pulmonary Gas Exchange Deficit in Normal Humans
We tested the hypothesis that transfusion can cause mild pulmonary dysfunction that has not been noticed clinically and is not sufficiently severe to fit the definition of transfusion-related acute lung injury.
Trends in Isolated Coronary Artery Bypass Grafting: An Analysis of the Society of Thoracic Surgeons Adult Cardiac Surgery Database
We used the Society of Thoracic Surgeons adult cardiac surgery database to characterize trends in patient characteristics and outcomes after CABG over the past decade.
Transfusion Immunomodulation – The Case for Leukoreduced and (Perhaps) Washed Transfusions
The present review will focus on two approaches, leukoreduction and saline washing, as means to reduce adverse transfusion outcomes.
Effect of Fresh Red Blood Cell Transfusions on Clinical Outcomes in Premature, Very Low-Birth-Weight Infants: The ARIPI Randomized Trial
In this trial, the use of fresh RBCs compared with standard blood bank practice did not improve outcomes in premature, very low-birth-weight infants requiring a transfusion.
Transfusion Thresholds and other Strategies for Guiding Allogeneic Red Blood Cell Transfusion
The purpose of this review is to compare clinical outcomes in patients randomised to restrictive versus liberal transfusion thresholds (triggers).
Prolonged Central Venous Desaturation Measured by Continuous Oximetry is Associated with Adverse Outcomes in Pediatric Cardiac Surgery
We demonstrate that ScvO₂ desaturations by continuous oximetry are associated with major adverse events in pediatric patients undergoing cardiac surgery.