Cardiac Surgery Outcomes in an Epicenter of the COVID-19 Pandemic
The outcomes demonstrated herein suggest that with proper infection control, isolation, and patient selection, results similar to those observed in non-COVID series can be replicated.
Extension of Cardiopulmonary Bypass Outside the Operating Room as A Short-Term Bridge to Recovery “The Poor Man’s ECMO”
This report describes the use of conventional cardiopulmonary bypass (CPB) circuit beyond the operating room to the critical care unit to provide cardiopulmonary support for patients requiring emergent resuscitation as well as short-term support for rest and recovery of the heart.
Neural Network-Based Modeling of the Number of Microbubbles Generated with Four Circulation Factors in Cardiopulmonary Bypass
The study demonstrated the importance of four circulation factors in the prediction of the number of MBs and its capacity to eliminate potential postsurgical complication risks.
Cardiopulmonary Bypass-Induced Coagulopathy in Paediatric Patients: The Role of Platelets in Postoperative Bleeding. A Preliminary Study
Postoperative bleeding in children undergoing cardiac surgery with CPB was linked to younger age, longer CPB duration and significant postoperative reduction in platelet count and function. Larger studies are needed to confirm our results and define strategies to reduce postoperative bleeding in these patients.
Validation of Transcutaneous Carbon Dioxide Monitoring Using an Artificial Lung During Adult Pulsatile Cardiopulmonary Bypass
Our experience in utilizing tcCO2 during CPB has demonstrated accuracy in estimating PaCO2 when compared to the gold standard arterial blood gas analysis, even during CO2 flooding of the surgical field.
Dose Estimation for Bivalirudin during Pediatric Cardiopulmonary Bypass
Bivalirudin infusion in children should be started after loading dose at rates greater than those used in adults. Dose in neonates remains uncertain because neither pharmacokinetics nor coagulation pharmacodynamics have been adequately characterized.
Red Blood Cell Exosome Hemoglobin Content Increases After Cardiopulmonary Bypass and Mediates Acute Kidney Injury in an Animal Model
These combined studies raise the potential for RBC-derived Exos, released during CPB, to target the kidney and mediate AKI.
Molecular Cardioprotection and the Role of Exosomes: The Future Is Not Far Away
This review discusses anesthetic implications of exosome production and the future micro-RNA applications for cardioprotection.
Engineered Protein Cages for Selective Heparin Encapsulation
The encapsulation is specific and the capsid-heparin assemblies display negligible hemolytic activity, indicating proper blood compatibility and promising possibilities for heparin antidote applications.
Health System Needs to Establish Cardiac Surgery Centers
Here, we describe the workforce, infrastructure, financial, and political needs and considerations from a health systems perspective to establish a cardiac surgery center.
Neurological Outcome After Minimally Invasive Coronary Artery Bypass Surgery (NOMICS): An Observational Prospective Cohort Study
The incidence of poor neurocognitive outcome, including stroke, POCD and postoperative ICU delirium until three months after Endo-CABG is low and comparable with PCI.
Ten Years of The Helsinki Declaration on Patient Safety in Anaesthesiology: An Expert Opinion on Peri-Operative Safety Aspects
With this publication we hope to further stimulate implementation of the Helsinki Declaration on Patient Safety in Anaesthesiology, as well as initiating relevant research in the future.