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This systematic review explored the findings of three pilot RCTs. Overall the hypothesis that NO delivered via the CPB circuit can provide cardioprotection has been supported by this study. There remains a significant gap in the evidence, further high-quality research is required in both the adult and paediatric populations.
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Plasma Fibrinogen Concentration is Correlated with Postoperative Blood Loss in Children undergoing Cardiac Surgery: A Retrospective Review
Post-CPB plasma fibrinogen concentration significantly influences blood loss in children undergoing cardiac surgery.
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A Survey of Patient Blood Management for Patients Undergoing Cardiac Surgery in Nine European Countries
PBM guidelines are not universally implemented in European cardiac surgery centres or countries, resulting in discrepancies in techniques and products used for a given clinical situation.
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