A Modified Protocol for Retrograde Cerebral Perfusion: Magnetic Resonance Spectroscopy in Pigs
Application of the modified RCP protocol significantly improved cerebral energy conservation during HCA and accelerated energy recovery after rewarming.
The Optimal Flow Rate for Antegrade Cerebral Perfusion During Deep Hypothermic Circulatory Arrest
Cerebral protection effects of ACP at 25 and 50 mL/kg/min were superior to that of ACP at 80 mL/kg/min as determined by cerebral markers, immunology, and histology.
Clinical Efficacy of Intermittent Pressure Augmented-Retrograde Cerebral Perfusion
IPA-RCP might provide more homogenous cerebral perfusion and a more effective oxygen supply to the brain with better clinical results than conventional RCP.
The Volatile Anesthetic Sevoflurane Inhibits Activation of Neutrophil Granulocytes During Simulated Extracorporeal Circulation
Sevoflurane inhibits granulocyte activation during ex vivo ECC and therefore has the potential to decrease the ECC-triggered inflammatory response.
Are Right Ventricular Risk Scores Useful?
The use of risk scores failed to predict the need of RV support after LVAD.
Low-Flow Antegrade Cerebral Perfusion Attenuates Early Renal and Intestinal Injury During Neonatal Aortic Arch Reconstruction
These results substantiate earlier suggestions that ACP provides more abdominal organ protection than DHCA in neonates undergoing aortic arch reconstruction.
Short-Acting P2Y12 Blockade to Reduce Platelet Dysfunction and Coagulopathy During Experimental Extracorporeal Circulation and Hypothermia
This experimental study tested P(2)Y(12) receptor blockade as an approach to protect platelets during ECC.
The Effects of Sevoflurane Anesthesia and Cardiopulmonary Bypass on Renal Function in Cyanotic and Acyanotic Children Undergoing Cardiac Surgery
We have concluded that renal function was not affected during open heart surgery with sevoflurane anesthesia, in both cyanotic and acyanotic children.
Safety of Training and Assessment in Operating Theatres – A Systematic Review and Meta-Analysis
This article establishes a systematic evidence base for the safety of training in the operating theatre.
Cold Reperfusion Before Rewarming Reduces Neurological Events after Deep Hypothermic Circulatory Arrest
Before rewarming, a 10-min period of cold perfusion significantly reduces incidence of NE.
Establishment of a Co-Culture Model for Studying Inflammation after Pediatric Cardiopulmonary Bypass: From Bench to Bedside
Our coculture model could be useful for studies on the mechanisms of CPB-induced inflammation.
The Early Inflammatory Response in A Mini-Cardiopulmonary Bypass System: A Prospective Randomized Study
The Medtronic RHS may induce less systemic inflammation than conventional CPB systems, particularly when cardiotomy suction was used, but it did not result in improved clinical benefit.