Fibrinogen Concentrate Therapy in Complex Cardiac Surgery
This study reports the initial clinical use of fibrinogen concentrate in complex cardiac surgery.
α-Tocopherol and Ascorbic Acid in Early Postoperative Period of Cardiopulmonary Bypass
To investigate whether α-tocopherol and ascorbic acid have effect on the suppression of inflammation in the early postoperative period after open heart surgery.
Impact of Transfusion of Autologous 7- versus 42-Day-Old AS-3 Red Blood Cells on Tissue Oxygenation and the Microcirculation in Healthy Volunteers
Transfusion of 1 unit of 42-day-stored RBCs to healthy subjects has no overt detrimental effect on tissue oxygenation or the microcirculation assessed by clinically available monitors.
Processed Residual Pump Blood in Cardiac Surgery: The Processed Residual Blood in Cardiac Surgery Trial
Ultrafiltration of residual CPB volume in adults undergoing isolated CABG surgery does not reduce the need for transfusion or bleeding.
Decreased Coronary Microvascular Reactivity after Cardioplegic Arrest in Patients with Uncontrolled Diabetes Mellitus
Uncontrolled diabetes is associated with endothelium-dependent and -independent vascular dysfunction of coronary arterioles.
Effect of Blower-Mister Devices on Vasoreactivity of Coronary Artery Bypass Grafts
Vessels exposed to the air and water stream of a blower-mister device showed a reduced vasoreactivity.
A Pilot Feasibility Trial of Allocation of Freshest Available Red Blood Cells versus Standard Care in Critically Ill Patients
We aimed to evaluate in intensive care unit (ICU) patients 1) the feasibility of allocating freshest available compatible RBCs versus standard care and 2) the suitability of this approach in the design of a large randomized controlled trial (RCT).
Prolonged Central Venous Desaturation Measured by Continuous Oximetry is Associated with Adverse Outcomes in Pediatric Cardiac Surgery
We demonstrate that ScvO₂ desaturations by continuous oximetry are associated with major adverse events in pediatric patients undergoing cardiac surgery.
Effect of Hospital Culture on Blood Transfusion in Cardiac Procedures
We sought to quantitate the contribution of hospital influence on individual surgeons' transfusion practices.
Fresh and Stored Red Blood Cell Transfusion Equivalently Induce Subclinical Pulmonary Gas Exchange Deficit in Normal Humans
We tested the hypothesis that transfusion can cause mild pulmonary dysfunction that has not been noticed clinically and is not sufficiently severe to fit the definition of transfusion-related acute lung injury.
Prospective Validation of the Vasoactive-Inotropic Score and Correlation to Short-Term Outcomes in Neonates and Infants after Cardiothoracic Surgery
In neonates and infants, a higher VIS at 48 h after cardiothoracic surgery is strongly associated with increased length of ventilation, and prolonged ICU and total hospital stay.
Changes in Microvascular Reactivity after Cardiopulmonary Bypass in Patients with Poorly Controlled versus Controlled Diabetes
Poorly controlled diabetes results in impaired arteriolar function before and after CPB.